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Nature Structural Biology  10, 585 - 587 (2003)
doi:10.1038/nsb0803-585

The IgA receptor complex: a two-for-one deal

Beth A Wurzburg & Theodore S Jardetzky

The authors are in the Department of Biochemistry, Molecular Biology and Cell Biology, Northwestern University, Evanston, Illinois 60208, USA. tedj@northwestern.edu

IgA triggers immune responses by binding to Fc receptors on cells of the immune system. The structure of IgA1-Fc in a complex with two molecules of FcalphaRI provides clues that may explain the selectivity of IgA-mediated immune events.

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RESEARCH
Insights into IgA-mediated immune responses from the crystal structures of human FcalphaRI and its complex with IgA1-Fc
Nature Article (05 Jun 2003)

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Nature Structural & Molecular Biology
ISSN: 1545-9993
EISSN: 1545-9985
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