The author is in the Department of Biology and the Curriculum in Genetics & Molecular Biology, University of North Carolina, Chapel Hill, North Carolina 27599, USA. smatson@bio.unc.edu
Two recent papers provide evidence that the Escherichia coli RecBCD complex, which unwinds double-stranded DNA to supply a substrate for recombination, has two helicase subunits that bind opposite DNA strands and move with opposite unwinding 'polarities'.
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