Josep Rizo is in the Departments of Biochemistry
and Pharmacology, The University of Texas Southwestern Medical Center,
Dallas, Texas 75390, USA.
jose@arnie.swmed.edu
The notion that SNARE proteins constitute the minimal machinery
for intracellular membrane fusion has been accepted by many scientists. An EPR
study now brings new structural data on the neuronal SNARE VAMP-2 and
emphasizes the importance of rigorous evidence before a hypothesis becomes a
dogma.
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