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Journal home Advance online publication Current issue Archive Press releases Supplements Focus Guide to authors Online submission Permissions For referees Free online issue Contact the journal Subscribe Advertising work@npg naturereprints About this site For librarians   NPG Resources Nature Nature Cell Biology Nature Reviews Molecular Cell Biology The EMBO Journal Nature Reports Avian Flu NPG Subject areas Biotechnology Cancer Chemistry Clinical Medicine Dentistry Development Drug Discovery Earth Sciences Evolution & Ecology Genetics Immunology Materials Science Medical Research Microbiology Molecular Cell Biology Neuroscience Pharmacology Physics Browse all publications News and Views Nature Structural Biology  10, 148 - 150 (2003) doi:10.1038/nsb0303-148 Structural lessons in DNA replication from the third domain of life Zvi Kelman1 & Jerard Hurwitz2 1  Zvi Kelman is in the Center for Advanced Research in Biotechnology, University of Maryland Biotechnology Institute, 9600 Gudelsky Drive, Rockville, Maryland 20850, USA. 2  Jerard Hurwitz is in the Department of Molecular Biology, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, Box 97, New York, New York 10021, USA. Correspondence should be addressed to Zvi Kelman kelman@umbi.umd.eduThe high-resolution structure of the N-terminal half of an archaeal MCM protein domain sheds light on the enzyme's helicase activity and its role in DNA replication. MORE ARTICLES LIKE THIS These links to content published by NPG are automatically generated REFERENCE Archaeal Chromosome Nature Encyclopaedia of Life Sciences  See all 2 matches for Reference REVIEWS Motors and switches: AAA+ machines within the replisome Nature Reviews Molecular Cell Biology Review (01 Nov 2002) A TALE OF TOROIDS IN DNA METABOLISM Nature Reviews Molecular Cell Biology Review Article (01 Oct 2000)  See all 3 matches for Reviews RESEARCH The structure and function of MCM from archaeal M. Thermoautotrophicum Nature Structural Biology Article (01 Mar 2003) Thymine-rich single-stranded DNA activates Mcm4/6/7 helicase on Y-fork and bubble-like substrates The EMBO Journal Article (17 Nov 2003)  See all 5 matches for Research  Top Abstract | Next Table of contents Full text Download PDF Send to a friend Open Innovation Challenges Novel Approaches to Protecting Maize from Insect Damage Deadline: Jan 31 2010 Reward: $20,000 USD The Seeker is looking for novel approaches to protecting maize from insect damage. This Challenge re... Optimizing Sub-cellular Localization Tags Deadline: Jan 31 2010 Reward: $20,000 USD The Seeker is looking for methods to optimize sub-cellular localization tags for protein expression.... More Challenges Powered by: nature jobs PhD Student Position in International PhD Program in Life Science, Munich International Max Planck Research School for Molecular and Cellular Life Sciences Munich 82152 Germany Postdoctoral Associate in Enzyme Biochemistry Cornell University Ithaca, New York More science jobs Post a job for free Figures & Tables See also: Article by Fletcher et al. Export citation Search buyers guide:   ADVERTISEMENT

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