Oliver J. Rando, Tian H. Chi and Gerald R. Crabtree are in the Department of Developmental Biology and the Department of Pathology, Stanford University, Stanford, California 94305, USA.
Two recent studies show that some ATP-dependent chromatin remodeling complexes are subject to control by a surprising set of regulators — phosphoinositols. These studies extend earlier observations in mammalian cells and suggest that second messengers are regulators of chromatin remodeling.
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