Nature Structural Biology
1, 201 - 203 (1994)
doi:10.1038/nsb0494-201
Deconvoluting serpinsRobert J. Fletterick1
& Mary E. McGrath2
1Department of Biochemistry & Biophysics, University of California, San Francisco, California, 94143-0448
2Khepri Pharmaceuti-cals, Inc., 260 Littlefield Avenue, South San Francisco, California, 94080-6902, USA The structure of an uncleaved serpin reveals a number of unusual features that have important implications for the mechanism of serpin action.
REFERENCES
- Wei, A., Rubin, H., Cooperman, B.S. & Christianson, D.W. Nature Struct. Biol. 1, 251−258 (1994). | PubMed | ISI | ChemPort |
- Zou, Z. et al. Science 263, 526−529 (1994). | PubMed | ISI | ChemPort |
- Ray, C.A. et al. Cell 69, 597−604 (1992). | Article | PubMed | ISI | ChemPort |
- Loebermann, H., Tokuoka, R., Deisenhofer, J. & Huber, R. J. Molec. Biol. 177, 531−556 (1984). | PubMed | ISI | ChemPort |
- Schechter, I. & Berger, A. Biochem. Biophys. Res. Com. 27, 157−162 (1967). | PubMed | ISI | ChemPort |
- Engh, R.A., Schulze, A.J., Huber, R. & Bode, W. Behring Inst. Mitt. 93, 41−62 (1993). | PubMed | ChemPort |
- Stein, P. et al. Nature 347, 99−102 (1990). | Article | PubMed | ISI | ChemPort |
- Baumann, U. et al. J. Molec. Biol. 218, 595 (1991). | PubMed | ISI | ChemPort |
- Baumann, U., Bode, W., Huber, R., Travis, J. & Potempa, J. J. Molec. Biol. 226, 1207 (1992). | PubMed | ISI | ChemPort |
- Mottonen, J. et al. Nature 255, 270−273 (1992). | Article |
- Schulze, A.J. et al. Eur. J. Biochem. 194, 51−56 (1990). | PubMed | ISI | ChemPort |
- Bjork, I., Ylinenjarvi, K., Olson, S. & Bock, P.E. J. biol. Chem. 267, 1976−1982 (1992). | PubMed | ISI | ChemPort |
- Schreuder, H.A. et al. Nature struct. Biol. 1, 48−55 (1994). | PubMed | ISI | ChemPort |
- Carrell, R.W., Stein, P.E., Fermi, G. & Wardell, M.R. Structure (in the press).
|
