Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Pain

Drug therapies for CP/CPPS: help or hype?

A recent network meta-analysis of α-blockers, antibiotics and other drug therapies for chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) found that they provided modest-to-no benefit for this condition, confirming previous findings. However, a casual reading of the article may give a false impression of the efficacy and appropriateness of these drugs.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

References

  1. Anothaisintawee, T. et al. Management of chronic prostatitis/chronic pelvic pain syndrome: a systematic review and network meta-analysis. JAMA 305, 78–86 (2011).

    Article  CAS  PubMed  Google Scholar 

  2. Song, F. et al. Methodological problems in the use of indirect comparisons for evaluations healthcare interventions: survey of published systematic reviews. BMJ 338, b1147 (2009).

    Article  PubMed  PubMed Central  Google Scholar 

  3. Curtis Nickel, J., Baranowski, A. P., Pontari, M., Berger, R. E. & Tripp, D. A. Management of men diagnosed with chronic prostatitis/chronic pelvic pain syndrome who have failed traditional management. Rev. Urol. 9, 63–72 (2007).

    CAS  PubMed  PubMed Central  Google Scholar 

  4. Nickel, J. C. et al. Alfuzosin and symptoms of chronic prostatitis–chronic pelvic pain syndrome. N. Engl. J. Med. 359, 2663–2673 (2008).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. Alexander, R. B. et al. Ciprofloxacin or tamsulosin in men with chronic prostatitis/chronic pelvic pain syndrome: a randomized, double-blind trial. Ann. Intern. Med. 141, 581–589 (2004).

    Article  CAS  PubMed  Google Scholar 

  6. Shoskes, D. A., Nickel, J. C. & Kattan, M. W. Phenotypically directed multimodal therapy for chronic prostatitis/chronic pelvic pain syndrome: a prospective study using UPOINT. Urology 75, 1249–1253 (2010).

    Article  PubMed  Google Scholar 

  7. Anderson, R. U., Wise, D., Sawyer, T. & Chan, C. Integration of myofascial trigger point release and paradoxical relaxation training treatment of chronic pelvic pain in men. J. Urol. 174, 155–160 (2005).

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Rodney U. Anderson.

Ethics declarations

Competing interests

The authors declare no competing financial interests.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Anderson, R., Nathanson, B. Drug therapies for CP/CPPS: help or hype?. Nat Rev Urol 8, 236–237 (2011). https://doi.org/10.1038/nrurol.2011.51

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nrurol.2011.51

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing