Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Review Article
  • Published:

Achieving urinary continence in children

Abstract

Achievement of urinary continence is an important developmental step that most children attain with the assistance of their parents and caregivers. Debate continues as to the best time to toilet train; in some Asian and African cultures children are trained as infants, while training at age 2–3 years is more typical in Western cultures. Infant voiding is not merely a spinal reflex, as the sensation of bladder filling is relayed to the brain. However, the ability of the brain to inhibit bladder contractions, and to achieve coordinated bladder contraction with sphincter relaxation, matures over time. While there is a concern that later toilet training may be responsible for an increase in urinary incontinence in children, no controlled studies on early versus late toilet training exist to evaluate this hypothesis. A number of medical conditions such as spina bifida, posterior urethral valves, cerebral palsy and autism can cause incontinence and difficulties in toilet training. The decision to start toilet training a child should take into account both the parents' expectation of how independent the child will be in terms of toileting, and the child's developmental readiness, so that a realistic time course for toilet training can be implemented.

Key Points

  • While an infant can be trained to control voiding, independent toileting is usually achieved in children aged between 2 and 4 years

  • Animal and human studies suggest that bladder emptying is regulated by the brain from the time of birth

  • Significant changes in a child's bladder and sphincter function occur at approximately 18 months of age

  • No prospective clinical study has compared the effects of early versus late toilet training

  • A number of medical disorders can cause difficulty in achieving urinary continence; management may include behavioral therapy or anticholinergic drugs

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Gorski, P. A. Toilet training guidelines: parents—the role of parents in toilet training. Pediatrics 103, 1362–1363 (1999).

    Google Scholar 

  2. Gorski, P. A. Toilet training guidelines: clinicians—the role of the clinician in toilet training. Pediatrics 103, 1364–1366 (1999).

    Google Scholar 

  3. Gorski, P. A. Toilet training guidelines: day care providers—the role of the day care provider in toilet training. Pediatrics 103, 1367–1368 (1999).

    Google Scholar 

  4. American Academy of Pediatrics Toilet Training Q&A. http://www.aap.org/publiced/BR_ToiletTrain.htm (2009).

  5. Milson, I. et al. in Incontinence 4th edn (ed. Abrams, P. et al.) 35–111 (Health Publication Ltd, Paris, 2009).

    Google Scholar 

  6. Boucke, L. Infant potty training: a gentle and primeval method adapted to modern living (White-Boucke, Lafayette, 2008).

    Google Scholar 

  7. Brazleton, T. B. A child oriented approach to toilet training. Pediatrics 29, 121–128 (1962).

    Google Scholar 

  8. Bakker, E. & Wyndaele, J. J. Changes in the toilet training of children during the last 60 years: the cause of an increase in lower urinary tract dysfunction? BJU Int. 86, 248–252 (2000).

    Article  CAS  Google Scholar 

  9. Accardo, P. Who's training whom? J. Pediatr. 149, 151–152 (2006).

    Article  Google Scholar 

  10. Kiddoo, D. et al. Evidence report/technology assessment No. 147. The effectiveness of different methods of toilet training for bowel and bladder control. AHRQ publication No. 07-E003 (Agency for Healthcare Research and Quality, Rockville, MD, 2006).

    Google Scholar 

  11. Foxx, R. M. & Azrin, N. H. Toilet training the retarded: a rapid program for day and nighttime independent toileting. (Research Press, Champaign, IL, 1974).

    Google Scholar 

  12. Jansson, U. B., Hanson, M., Sillen, U. & Hellstrom, A. L. Voiding pattern and acquisition of bladder control from birth to age 6 years—a longitudinal study. J. Urol. 174, 289–293 (2005).

    Article  Google Scholar 

  13. Largo, R. H. & Stutzle, W. Longitudinal study of bowel and bladder control by day and at night in the first six years of life. I: epidemiology and interrelations between bowel and bladder control. Devel. Med. Child Neurol. 19, 598–606 (1977).

    Article  CAS  Google Scholar 

  14. Largo, R. H. & Stutzle, W. Longitudinal study of bowel and bladder control by day and at night in the first six years of life. II: The role of potty training and the child's initiative. Devel. Med. Child Neurol. 19, 607–613 (1977).

    Article  CAS  Google Scholar 

  15. Largo, R. H., Molinari, L., von Siebenthal, K. & Wolfenberger, U. Does a profound change in toilet-training affect development of bowel and bladder control? Devel. Med. Child Neurol. 38, 1106–1116 (1996).

    Article  CAS  Google Scholar 

  16. Oppel, W. C., Harper, P. A. & Rider, R. V. The age of attaining bladder control. Pediatrics 42, 614–626 (1968).

    CAS  PubMed  Google Scholar 

  17. Blum, N. J., Taubman, B. & Nemeth, N. Relationship between age at initiation of toilet training and duration of training: a prospective study. Pediatrics 111, 810–814 (2003).

    Article  Google Scholar 

  18. deVries, M. W. & deVries, M. R. Cultural relativity of toilet training readiness: a perspective from East Africa. Pediatrics 60, 170–177 (1977).

    CAS  PubMed  Google Scholar 

  19. Duong, T. H., Jansson, U. B., Holmdahl, G., Sillen, U. & Hellstrom, A. L. Development of bladder control in the first year of life in children who are potty trained early. J. Pediatr. Urol. doi: 10.1016/jpurol.2009.11.002.

  20. Schum, T. R. et al. Sequential acquisition of toilet-training skills: a descriptive study of gender and age differences in normal children. Pediatrics 109, e48 (2002).

    Article  Google Scholar 

  21. Largo, R. H., Molinari, L., von Siebenthal, K. & Wolfensberger, U. Development of bladder and bowel control: significance of prematurity, perinatal risk factors, psychomotor development and gender. Eur. J. Pediatr. 158, 115–122 (1999).

    Article  CAS  Google Scholar 

  22. Schonwald, A., Sherritt, L., Stadtler, A. & Bridgemohan, C. Factors associated with difficult toilet training. Pediatrics 113, 1753–1757 (2004).

    Article  Google Scholar 

  23. Blum, N. J., Taubman, B. & Nemeth, N. Why is toilet training occurring at older ages? A study of factors associated with later training. J. Pediatr. 145, 107–111 (2004).

    Article  Google Scholar 

  24. Gladh, G., Persson, D., Mattsson, S. & Lindstrom, S. Voiding patterns in healthy newborns. Neurourol. Urodyn. 19, 177–184 (2000).

    Article  CAS  Google Scholar 

  25. Sillen, U. Bladder function in healthy neonates and its development during infancy. J. Urol. 166, 2376–2381 (2001).

    Article  CAS  Google Scholar 

  26. Yeung, C. K. et al. Some new insights into bladder function in infancy. Br. J. Urol. 76, 235–240 (1995).

    Article  CAS  Google Scholar 

  27. Yeung, C. K., Godley, M. L., Dhillon, H. K., Duffy, P. G. & Ransley, P. G. Urodynamic patterns in infants with normal lower urinary tracts or primary vesico-ureteric reflux. Br. J. Urol. 81, 461–467 (1998).

    Article  CAS  Google Scholar 

  28. Bachelard, M. et al. Urodynamic pattern in asymptomatic infants: siblings of children with vesicoureteral reflux. J. Urol. 162, 1733–1738 (1999).

    Article  CAS  Google Scholar 

  29. Capek, K. & Jelinek, J. The development of the control of water metabolism: I. The excretion of urine in young rats. Physiol. Bohemoslov. 5, 91–96 (1956).

    CAS  PubMed  Google Scholar 

  30. Maggi, C. A., Santicioli, P. & Meli, A. Postnatal development of micturition reflex in rats. Am. J. Physiol. 250, R926–R931 (1986).

    CAS  PubMed  Google Scholar 

  31. Kruse, M. N. & de Groat, W. C. Micturition reflexes in decerebrate and spinalized neonatal rats. Am. J. Physiol. 258, R1508–R1511 (1990).

    CAS  PubMed  Google Scholar 

  32. de Groat, W. C. et al. Developmental and injury induced plasticity in the micturition reflex pathway. Behav. Brain Res. 92, 127–140 (1998).

    Article  CAS  Google Scholar 

  33. Araki, I. & de Groat, W. C. Developmental synaptic depression underlying reorganization of visceral reflex pathways in the spinal cord. J. Neurosci. 17, 8402–8407 (1997).

    Article  CAS  Google Scholar 

  34. de Groat, W. C. Plasticity of bladder reflex pathways during postnatal development. Physiol. Behav. 77, 689–692 (2002).

    Article  CAS  Google Scholar 

  35. Wu, H. Y. & de Groat, W. C. Maternal separation uncouples reflex from spontaneous voiding in rat pups. J. Urol. 175, 1148–1151 (2006).

    Article  Google Scholar 

  36. Ng, Y. K., Wu, H. Y., Lee, K. H. & Yeung, C. K. Bladder reduction surgery accelerates the appearance of spontaneous voiding in neonatal rats. J. Urol. 183, 370–377 (2010).

    Article  Google Scholar 

  37. Boehm, J. J. & Haynes, J. L. Bacteriology of “midstream catch” urines. Am. J. Dis. Child 111, 366–369 (1966).

    Article  CAS  Google Scholar 

  38. Vollmer, H. A new reflex in young infants. AMA J. Dis. Child. 95, 481–484 (1958).

    CAS  PubMed  Google Scholar 

  39. Zderic, S. A. et al. Developmental aspects of bladder contractile function: sensitivity to extracellular calcium. Pharmacology 43, 61–68 (1991).

    Article  CAS  Google Scholar 

  40. Zderic, S. A. et al. Developmental aspects of bladder contractile function: evidence for an intracellular calcium pool. J. Urol. 150, 623–625 (1993).

    Article  CAS  Google Scholar 

  41. Zderic, S. A. et al. Developmental aspects of excitation contraction coupling of rabbit bladder smooth muscle. J. Urol. 152, 679–681 (1994).

    Article  CAS  Google Scholar 

  42. Wu, H. Y., Zderic, S. A., Wein, A. J. & Chacko, S. Decrease in maximal force generation in the neonatal mouse bladder corresponds to shift in myosin heavy chain isoform composition. J. Urol. 171, 841–844 (2004).

    Article  CAS  Google Scholar 

  43. Szell, E. A., Somogyi, G. T., de Groat, W. C. & Szigeti, G. P. Developmental changes in spontaneous smooth muscle activity in the neonatal rat urinary bladder. Am. J. Physiol. Regul. Integr. Comp. Physiol. 285, R809–R816 (2003).

    Article  CAS  Google Scholar 

  44. Ng, Y. K., de Groat, W. C. & Wu, H. Y. Smooth muscle and neural mechanisms contributing to the down-regulation of neonatal rat spontaneous bladder contractions during postnatal development. Am. J. Physiol. Regul. Integr. Comp. Physiol. 292, R2100–R2112 (2007).

    Article  CAS  Google Scholar 

  45. Bakker, E., van Gool, J. D., van Sprundel, M., van der Auwera, C. & Wyndaele, J. J. Results of a questionnaire evaluating the effects of different methods of toilet training on achieving bladder control. BJU Int. 90, 456–461 (2002).

    Article  CAS  Google Scholar 

  46. Joinson, C. et al. A prospective study of age at initiation of toilet training and subsequent daytime bladder control in school-age children. J. Dev. Behav. Pediatr. 30, 385–393 (2009).

    Article  Google Scholar 

  47. Tekgul, S. et al. in Incontinence 4th edn (ed. Abrams, P. et al.) 701–792 (Health Publication Ltd, Paris, 2009).

    Google Scholar 

  48. Hellstrom, A. L. Influence of potty training habits on dysfunctional bladder in children. Lancet 356, 1787 (2000).

    Article  CAS  Google Scholar 

  49. Park, J. M., Bloom, D. A. & Mcguire, E. J. The guarding reflex revisited. Br. J. Urol. 80, 940–945 (1997).

    Article  CAS  Google Scholar 

  50. Vermandel, A., van Kampen, M., van Gorp, C. & Wyndaele, J. J. How to toilet train healthy children? A review of the literature. Neurourol. Urodyn. 27, 162–166 (2008).

    Article  Google Scholar 

  51. Fitzgerald, M. P. et al. Childhood urinary symptoms predict adult overactive bladder symptoms. J. Urol. 175, 989–993 (2006).

    Article  Google Scholar 

  52. Minassian, V. A., Lovatsis, D., Pascali, D., Alarab, M. & Drutz, H. P. Effect of childhood dysfunctional voiding on urinary incontinence in adult women. Obstet. Gynecol. 107, 1247–1251 (2006).

    Article  Google Scholar 

  53. Iddon, J. L., Morgan, D. J. R., Loveday, C., Sahakian, B. J. & Pickard, J. Neuropsychological profile of young adults with spina bifida with or without hydrocephalus. J. Neurol. Neurosurg. Psychiatry 75, 1112–1118 (2004).

    Article  CAS  Google Scholar 

  54. Smith, G. H., Canning, D. A., Schulman, S. L., Snyder, H. M. III & Duckett, J. W. The long-term outcome of posterior urethral valves treated with primary valve ablation and observation. J. Urol. 155, 1730–1734 (1996).

    Article  CAS  Google Scholar 

  55. Koff, S. A., Mutabagani, K. H. & Jayanthi, R. The valve bladder syndrome: pathophysiology and treatment with nocturnal bladder emptying. J. Urol. 167, 291–297 (2002).

    Article  Google Scholar 

  56. Decter, R. M. et al. Urodynamic assessment of children with cerebral palsy. J. Urol. 138, 1110–1112 (1987).

    Article  CAS  Google Scholar 

  57. Silva, J. A. F., Alvares, R. A., Barboza, A. L. & Monteiro, R. T. M. Lower urinary tract dysfunction in children with cerebral palsy. Neurourol. Urodyn. 28, 959–963 (2009).

    Article  Google Scholar 

Download references

Acknowledgements

Charles P. Vega, University of California, Irvine, CA, is the author of and is solely responsible for the content of the learning objectives, questions and answers of the MedscapeCME-accredited continuing medical education activity associated with this article.

Author information

Authors and Affiliations

Authors

Ethics declarations

Competing interests

The author declares no competing financial interests.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Wu, HY. Achieving urinary continence in children. Nat Rev Urol 7, 371–377 (2010). https://doi.org/10.1038/nrurol.2010.78

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nrurol.2010.78

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing