Review
Nature Reviews Urology 6, 612-621 (November 2009) | doi:10.1038/nrurol.2009.202
Subject Categories: Urinary incontinence, urodynamics and lower urinary tract dysfunction | Trauma and reconstruction
The bladder extracellular matrix. Part II: regenerative applications
Karen J. Aitken & Darius J. Bägli About the authors
Abstract
Bladder regeneration is a long-sought goal that could provide alternatives to cystoplasty using non-urological tissues. Regeneration might be achieved in different ways, such as seeding matrices with stem cells or conventional cells, or repopulation of the matrix by the body's own reservoir of cells. Consideration of how the extracellular matrix directs cell behavior will be crucial to the success of regenerative therapies.
Author affiliations
K. J. Aitken
&
D. J. Bägli
Divisions of Developmental & Stem Cell Biology, and Urology, The Hospital For Sick Children, University of Toronto, ON, Canada. (K. J. Aitken, D. J. Bägli).
Correspondence to: D. J. Bägli darius.bagli@sickkids.ca
