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  • Case Study
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A case of florid cystitis glandularis

Abstract

Background A 32-year-old healthy woman from China was diagnosed with a bladder mass during pelvic ultrasonography, carried out during the work-up of a miscarriage. Cystoscopy by the Department of Obstetrics and Gynecology confirmed the presence of a bladder mass, after which she was referred to our department for evaluation and management. The patient was asymptomatic at presentation. She denied urologic symptoms and did not have a history of smoking or industrial exposure to carcinogens.

Investigations Laboratory test results and urine studies were unremarkable. Cytology revealed benign cells with numerous micro-organisms. Intravenous pyelography revealed a 1 × 2 cm filling defect in the mid posterior bladder compatible with a mass. There were no upper urinary tract defects. We performed cystoscopy with transurethral resection of the bladder tumor.

Diagnosis Pathology revealed cystitis glandularis.

Management The patient was followed up with repeat cystoscopy after 4 months; there was no evidence of recurrence. She was scheduled for surveillance after a further 3 months, but was lost to follow-up.

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Figure 1: Intravenous pyelogram
Figure 2: Accumulation of epithelial cells separated from the surface epithelium by a stromal border, also known as a von Brunn cell nest

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Acknowledgements

The authors would like to thank Jonathan Epstein, MD and the Department of Pathology for help with selection of this case, and with preparation of the histologic slide featured in the figure section.

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Correspondence to Michelle Jo Semins.

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The authors declare no competing financial interests.

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Semins, M., Schoenberg, M. A case of florid cystitis glandularis. Nat Rev Urol 4, 341–345 (2007). https://doi.org/10.1038/ncpuro0814

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