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Research Highlights
Nature Reviews Urology 3, 120 (1 March 2006) | doi:10.1038/ncpuro0398
Vitamin D analog BXL628 arrests prostate growth in patients with benign prostatic hyperplasia
Abstract
Colli E et al. (2006) BXL628, a novel vitamin D3 analog arrests prostate growth in patients with benign prostatic hyperplasia: a randomized clinical trial. Eur Urol 49: 82–86 Proliferation of prostate cells, as in benign prostatic hyperplasia (BPH), is inhibited by binding of agonists such as vitamin D3 to the vitamin D receptor expressed on the prostate cell surface.
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