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Research Highlights
Nature Reviews Urology 3, 123 (1 March 2006) | doi:10.1038/ncpuro0418
Ixabepilone shows activity in hormone-refractory prostate cancer
Abstract
Hussain et al. (2005) Ixabepilone (epothilone B analogue BMS-247550) is active in chemotherapy-naive patients with hormone-refractory prostate cancer: a Southwest Oncology Group trial S0111. J Clin Oncol 23: 8724–8792 Taxanes stabilize the microtubules involved in cell division, thereby inhibiting tumor growth.
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