Table of contents
July 2005 Volume 2 No 7
Editorial
Viewpoint
Overactive bladder: drug therapy versus nerve stimulation
310Overactive bladder is a common urologic disorder with a number of etiologies and evolving treatment options. The two primary management strategies are drug therapy and sacral neurostimulation, both areas of recent developments with the emergence of new medications and refinement of surgical techniques. In this Viewpoint, Apurba Pathak and Sherif Aboseif discuss the relative merits, and drawbacks, of these very different approaches.
Research Highlights
The treatment of early prostate cancer: 10-year follow-up
312Coached maternal pushing might cause postpartum pelvic floor dysfunction
312Randomized clinical trial reveals effective new male hormonal contraceptive regimen
312Vaccine combined with EBRT effective for patients with localized prostate cancer
313The Ter mutation in the dead end gene is responsible for germ cell loss and testicular germ cell tumors
313Prenatal phthalate exposure decreases anogenital distance in human males
314Predictive value of procalcitonin for vesicoureteral reflux
314Positive clinical data on 80 W laser vaporization of the prostate
315Emergency extracorporeal shock wave lithotripsy for symptomatic ureteral stones
315CpG hypermethylation of the GSTP1 promoter in prostate cancer patients from different ethnic groups
316New salvage treatment for advanced urothelial tract cancers
316Encouraging laparoscopic renal cryoablation outcomes at 3 years
316Practice Points
Do elderly patients with advanced urothelial carcinoma benefit from platinum-based chemotherapy?
318Can a point-of-care proteomic assay increase the accuracy of cystoscopy?
320Does dose escalation using conformal radiotherapy improve control of prostate cancer?
322Do patients with penile carcinoma benefit from immediate resection of clinically occult lymph node metastases?
324Can wetting and voiding disorders in children be evaluated using a standard questionnaire?
326Reviews
The current status of laparoscopic retroperitoneal lymph node dissection for non-seminomatous germ-cell tumors
330Retroperitoneal lymph node dissection (RPLND) is used in both the staging and management of non-seminomatous germ-cell tumors. Although a number of advantages of the laparoscopic approach have been reported over open RPLND, its use has not been supported by formal internal review board-approved studies. Brett Carver and Joel Sheinfeld discuss RPLND in the management of these tumors, both before and after chemotherapy.
doi:10.1038/ncpuro0226 | Full Text | PDF (108K)
The role of lymphadenectomy in prostate cancer
336In this review, Fiona Burkhard and colleagues discuss the use of retroperitoneal lymph node dissection in both the staging and treatment of prostate cancer. Their discussion covers the preoperative methods used to assess lymph nodes and compares the merits and drawbacks of extended compared to limited lymphadenectomy when staging prostate cancer, and their possible influence on patient survival.
doi:10.1038/ncpuro0245 | Full Text | PDF (336K)
Therapy Insight: management of urology patients taking long-term warfarin anticoagulation therapy
343Invasive urologic procedures carry the potential to cause hemorrhaging, the risk of which is greater for patients receiving long-term anticoagulation therapy. Paul Daniels reviews these risks and the management options that can be used to balance the risks of hemorrhage against the problems of venous thromboembolism, if anticoagulation therapy is stopped in this group of patients.
doi:10.1038/ncpuro0204 | Full Text | PDF (132K)
Case Study

Bilateral kidney stones with ureteropelvic junction obstruction
351doi:10.1038/ncpuro0231 | Full Text | PDF (178K)


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,
Ali Güne