Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Case Study
  • Published:

A case of undiagnosed tethered cord syndrome aggravated by transurethral prostate resection

Abstract

Background A 68-year-old man presented with a history of significant urinary urge incontinence, pollakiuria, and weak bladder sensation. He also reported mild fecal incontinence and a hypotrophic and slightly weaker left leg. At 63 years of age he had presented to a urologist for treatment of irritative lower urinary tract symptoms and incontinence. A transurethral resection of the prostate had been performed. After the operation, the symptoms had persisted and the incontinence seriously worsened.

Investigations Clinical neurologic examination, videourodynamic examination, neurophysiologic examination, and MRI of the spinal cord.

Diagnosis Neurogenic bladder dysfunction caused by adult tethered cord syndrome with myelon up to S2 level, spina bifida occulta, and lipoma infiltrating the conus medullaris.

Management Conservative anticholinergic treatment failed, and injection of botulinum-A toxin is planned.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Cystometry chart during the ice-water test showed a strong involuntary contraction of the bladder up to a pressure of 240 cm H2O after 1 minute.
Figure 2: Filling cystometry chart.
Figure 3: T2-weighted sagittal MRI of the lower spinal cord.
Figure 4: T1-weighted axial MRI of the sacrum.
Figure 5: Examination algorithm.

References

  1. Iskandar BJ et al. (1998) Congenital tethered spinal cord syndrome in adults. J Neurosurg 88: 958–961

    Article  CAS  Google Scholar 

  2. Lapsiwala SB and Iskandar BJ (2004) The tethered cord syndrome in adults with spina bifida occulta. Neurol Res 26: 735–740

    Article  Google Scholar 

  3. Huttmann S et al. (2001) Surgical management of tethered spinal cord in adults: report of 54 cases. J Neurosurg Spine 95: 173–178

    Article  CAS  Google Scholar 

  4. Pang D and Wilberger JE Jr (1982) Tethered cord syndrome in adults. J Neurosurg 57: 32–47

    Article  CAS  Google Scholar 

  5. Yamada S et al. (2004) Symptomatic protocols for adult tethered cord syndrome. Neurol Res 26: 741–744

    Article  Google Scholar 

  6. Haro H et al. (2004) Long-term outcomes of surgical treatment for tethered cord syndrome. J Spinal Disord Tech 17: 16–20

    Article  Google Scholar 

  7. Adamson AS et al. (1993) Tethered cord syndrome: an unusual cause of adult bladder dysfunction. Br J Urol 71: 417–421

    Article  CAS  Google Scholar 

  8. van Leeuwen R et al. (2001) Surgery in adults with tethered cord syndrome: outcome study with independent clinical review. J Neurosurg Spine 94: 205–209

    Article  CAS  Google Scholar 

  9. Giddens JL et al. (1999) Urodynamic findings in adults with the tethered cord syndrome. J Urol 161: 1249–1254

    Article  CAS  Google Scholar 

  10. Reitz A et al. (2004) European experience of 200 cases treated with botulinum-A toxin injections into the detrusor muscle for urinary incontinence due to neurogenic detrusor overactivity. Eur Urol 45: 510–515

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Sönke Boy.

Ethics declarations

Competing interests

The authors declare no competing financial interests.

Glossary

HYPESTHESIA

Diminished ability to perceive tactile stimuli

HYPALGESIA

Diminished ability to perceive painful stimuli

CONUS MEDULLARIS

The cone-shaped lower end of the spinal cord

SPINA BIFIDA OCCULTA

A congenital condition representing a set of 'covered' spinal cord lesions that include intraspinal lipoma, lipomyelomeningocele, split cord malformation, meningocele manqué, ectodermal inclusion tumor or cyst, neurenteric cyst and tight filum terminale

FILUM TERMINALE

Threadlike appendage to the lower spinal cord

Rights and permissions

Reprints and permissions

About this article

Cite this article

Boy, S., Reitz, A., Curt, A. et al. A case of undiagnosed tethered cord syndrome aggravated by transurethral prostate resection. Nat Rev Urol 2, 199–204 (2005). https://doi.org/10.1038/ncpuro0140

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1038/ncpuro0140

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing