Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Prostate cancer

Growth of AS in the USA signals reduction in overtreatment

Nature Reviews Urology volume 12, pages 604–605 (2015)Cite this article

Subjects

Is the overtreatment era drawing to a close? New data from the CaPSURE study demonstrate that US urologists are now firmly embracing active surveillance for low-risk prostate cancer.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Overall trends in the management of localized prostate cancer in the CaPSURE database, 1990–2013.

References

  1. Barocas, D. A. et al. The effect of the United States Preventive Services Task Force grade D recommendation against screening for prostate cancer on incident prostate cancer diagnoses in the US. J. Urol. http://dx.doi.org/10.1016/j.juro.2015.06.075.

  2. Bhindi, B. et al. Impact of the, U. S. Preventive Services Task Force recommendations against prostate specific antigen screening on prostate biopsy and cancer detection rates. J. Urol. 193, 1519–1524 (2015).

    Article  Google Scholar 

  3. Gulati, R. et al. Expected population impacts of discontinued prostate-specific antigen screening. Cancer 120, 3519–3526 (2014).

    Article  Google Scholar 

  4. Cooperberg, M. R., Broering, J. M. & Carroll, P. R. Time trends and local variation in primary treatment of localized prostate cancer. J. Clin. Oncol. 28, 1117–1123 (2010).

    Article  Google Scholar 

  5. Cooperberg, M. R. & Carroll, P. R. Trends in management for patients with localized prostate cancer, 1990–2013. JAMA 314, 80–2 (2015).

    Article  CAS  Google Scholar 

  6. Womble, P. R. et al. Contemporary use of initial active surveillance among men in Michigan with low-risk prostate cancer. Eur. Urol. 67, 44–50 (2015).

    Article  Google Scholar 

  7. Weerakoon, M. et al. The current use of active surveillance in an Australian cohort of men: a pattern of care analysis from the Victorian Prostate Cancer Registry. BJU Int. 115 (Suppl. 5), 50–56 (2015).

    Article  Google Scholar 

  8. Loeb, S., Berglund, A. & Stattin, P. Population-based study of utilization and determinants of active surveillance and watchful waiting for low- and intermediate-risk prostate cancer. J. Urol. 190, 1742–1749 (2013).

    Article  Google Scholar 

  9. Loeb, S., Folkwaljon, Y., Bratt, O., Robinson, D. & Stattin, P. E. Expanding use of active surveillance: data from the National Prostate Cancer Register (NPCR) of Sweden. J. Urol. 193, e512 (2015).

    Google Scholar 

  10. Murphy, D. G. et al. The Melbourne Consensus Statement on the early detection of prostate cancer. BJU Int. 113, 186–188 (2014).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Division of Cancer Surgery, University of Melbourne, Peter MacCallum Cancer Centre, St Andrews Place, East Melbourne, 3002, VIC, Australia

    Declan G. Murphy

  2. Department of Urology, Population Health, and the Laura & Isaac Perlmutter Cancer Center, New York University, NYU Langone Medical Center, 550 First Avenue, New York, 10016, NY, USA

    Stacy Loeb

Authors
  1. Declan G. Murphy
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Stacy Loeb
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Declan G. Murphy.

Ethics declarations

Competing interests

The authors declare no competing financial interests.

PowerPoint slides

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Murphy, D., Loeb, S. Growth of AS in the USA signals reduction in overtreatment. Nat Rev Urol 12, 604–605 (2015). https://doi.org/10.1038/nrurol.2015.236

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nrurol.2015.236

This article is cited by

Search

Advanced search

Quick links

Nature Briefing: Cancer

Sign up for the Nature Briefing: Cancer newsletter — what matters in cancer research, free to your inbox weekly.

Get what matters in cancer research, free to your inbox weekly. Sign up for Nature Briefing: Cancer