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Nature Reviews Rheumatology 2, 7–8 (1 January 2006) | doi:10.1038/ncprheum0060

Use of alendronate to prevent femoral-head collapse

Katherine Sole

Lai K-A et al. (2005) The use of alendronate to prevent early collapse of the femoral head in patients with nontraumatic osteonecrosis: a randomized clinical study. J Bone Joint Surg Am 87: 2155–2159 Osteonecrosis of the femoral head is responsible for a large proportion of primary total hip replacements.