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Neurodegenerative disease

Frontotemporal dementia—time to target inflammation?

Nature Reviews Neurology volume 9, pages 304–305 (2013)Cite this article

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Systemic inflammation has been associated with dementia. A new study has found an increased rate of autoimmune disorders and elevated serum levels of tumour necrosis factor in patients with frontotemporal dementia associated with TDP-43 pathology. These findings help in understanding disease mechanisms and in identification of biomarkers of this heterogeneous disease.

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  1. Neuroscience Research Australia, Barker Street, Randwick, 2031, NSW, Australia

    Olivier Piguet

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  1. Olivier Piguet
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Piguet, O. Frontotemporal dementia—time to target inflammation?. Nat Rev Neurol 9, 304–305 (2013). https://doi.org/10.1038/nrneurol.2013.84

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