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Parkinson disease

Parkinson disease clinical subtypes and their implications

Despite the emergence of genetic and molecular approaches, disease categorization on the basis of clinical features remains an appealing approach, especially where the molecular mechanisms are poorly understood. A new study supports distinct clinical subtypes of Parkinson disease that could have implications for understanding the etiology of this condition.

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Figure 1: Biochemical senescence and pathogenetic pathways to cell death in Parkinson disease.

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Correspondence to Anthony H. V. Schapira.

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Schapira, A., Schrag, A. Parkinson disease clinical subtypes and their implications. Nat Rev Neurol 7, 247–248 (2011). https://doi.org/10.1038/nrneurol.2011.40

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