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Parkinson disease

Deep brain stimulation in Parkinson disease—what went wrong?

Nature Reviews Neurology volume 6, pages 535–536 (2010)Cite this article

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Deep brain stimulation of the subthalamic nucleus or the internal pallidum can be an effective treatment for the disabling motor complications arising from dopaminergic treatment for Parkinson disease. The subthalamic nucleus has emerged as the preferred target for such treatment; however, no data exist to guide the choice between these two sites.

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Authors and Affiliations

  1. Department of Psychiatry and Neurology, Movement Disorders Unit, University Hospital Grenoble, 38043 Grenoble, 9, Cedex, France

    Paul Krack

  2. Unit of Functional Neurosurgery, University College London Institute of Neurology, Box 146, Queen Square, London, WC1N 3BG, UK

    Marwan I. Hariz

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  1. Paul Krack
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  2. Marwan I. Hariz
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Correspondence to Paul Krack.

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Competing interests

P. Krack has received research support and reimbursement of travel costs to scientific meetings from Medtronic. M. I. Hariz has received honoraria and travel expenses from Medtronic for speaking at meetings.

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Krack, P., Hariz, M. Deep brain stimulation in Parkinson disease—what went wrong?. Nat Rev Neurol 6, 535–536 (2010). https://doi.org/10.1038/nrneurol.2010.141

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