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Nature Reviews Neurology 5, 582–583 (1 November 2009) | doi:10.1038/nrneurol.2009.163

Stroke: The vacuum cleaner for stroke

Kristine A. Blackham & Robert W. Tarr

A 'vacuum cleaning' for the brain following stroke has been shown to remove the clot, although cleanliness may not be the sole requisite to restore a healthy brain, as investigators discovered with the results of the Penumbra Pivotal Stroke Trial, reported in Stroke. In this prospective, single-cohort, phase II, international, multicenter study the safety and effectiveness of the Penumbra System|[reg]| aspiration catheter (Penumbra, Inc.