Approaching a renaissance in coma research responsibly

Paul M Matthews

doi:10.1038/ncpneuro0916 | Full Text | PDF (131K)

MRZ reaction could distinguish patients with NMO from those with MS

doi:10.1038/ncpneuro0890 | Full Text | PDF (73K)

Vitamin D supplements could guard against stroke

doi:10.1038/ncpneuro0891 | Full Text | PDF (73K)

Antisense RNA upregulates -secretase 1 in Alzheimer disease

doi:10.1038/ncpneuro0893 | Full Text | PDF (85K)

Metabolic syndrome predicts resistance to thrombolysis in stroke patients

doi:10.1038/ncpneuro0892 | Full Text | PDF (74K)

Disrupted calcium homeostasis implicated in Alzheimer disease pathogenesis

doi:10.1038/ncpneuro0894 | Full Text | PDF (84K)

Potential therapeutic role of microRNAs in glioblastoma multiforme

doi:10.1038/ncpneuro0896 | Full Text | PDF (74K)

Does plaque clearance halt progression of Alzheimer disease?

doi:10.1038/ncpneuro0897 | Full Text | PDF (74K)

In briefs

doi:10.1038/ncpneuro0889 | Full Text | PDF (124K)

Neuroleptic discontinuation during dementia care: a recent trial and its implications for practice

Chiadi U Onyike

doi:10.1038/ncpneuro0884 | Full Text | PDF (163K)

Pushing or pulling to predict falls in Parkinson disease?

Christopher J Hass, Bastiaan R Bloem and Michael S Okun

doi:10.1038/ncpneuro0912 | Full Text | PDF (161K)

Optic neuritis and the risk of multiple sclerosis—what can we learn from a brain MRI scan?

Steven E Feldon

doi:10.1038/ncpneuro0911 | Full Text | PDF (157K)

Kleine–Levin syndrome: a disease in its own right?

Jacob Taylor, Crystal Watkins and Adam Kaplin

doi:10.1038/ncpneuro0900 | Full Text | PDF (164K)

Transcranial ultrasound in the diagnosis of Parkinson's disease

WR Wayne Martin

doi:10.1038/ncpneuro0859 | Full Text | PDF (158K)

The hyperdense internal carotid artery sign: a specific but limited marker of occlusion in stroke

Michael D Hill

doi:10.1038/ncpneuro0899 | Full Text | PDF (156K)

Eye signs in patients with parkinsonism: do they predict the development of multiple system atrophy?

William A Fletcher

doi:10.1038/ncpneuro0885 | Full Text | PDF (164K)

Neuroimaging, impaired states of consciousness, and public outreach

Judy Illes, Patricia W Lau and Joseph T Giacino

Functional neuroimaging is emerging as a novel tool to evaluate patients with disorders of consciousness. This Viewpoint looks at one of the most vexing ethical challenges resulting from this development: how should doctors react if families request a functional MRI scan for a loved one who is in a limited state of consciousness?

doi:10.1038/ncpneuro0888 | Full Text | PDF (174K)

The changing spectrum of coma

Steven Laureys and Mélanie Boly

The concept of consciousness has evolved as technology has progressed, and our understanding of coma and disorders of consciousness has deepened accordingly. In this Viewpoint, Steven Laureys traces the beginnings of coma research and shows how the introduction of functional neuroimaging has revolutionized this field.

doi:10.1038/ncpneuro0887 | Full Text | PDF (194K)

Neurological manifestations of Waldenström macroglobulinemia

Joachim M Baehring, Ephraim P Hochberg, Noopur Raje, Matthew Ulrickson and Fred H Hochberg

Waldenstrom's macroglobulinemia—a condition that is characterized by overproduction of IgM antibodies and most commonly occurs in lymphoplasmacytic lymphoma—is often accompanied by nervous system complications, such as peripheral neuropathy or complications related to serum hyperviscosity. This Review provides an overview of the diagnosis and treatment of such neurological manifestations.

doi:10.1038/ncpneuro0917 | Full Text | PDF (593K)