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Research Highlights
Nature Reviews Neurology 3, 592 (1 November 2007) | doi:10.1038/ncpneuro0593
Lacunar lesion burden predicts cognitive impairment and disability in CADASIL
Abstract
Viswanathan A et al. (2007) Lacunar lesions are independently associated with disability and cognitive impairment in CADASIL. Neurology 69: 172–179 Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is caused by mutation of the NOTCH3 gene and is considered a model of 'pure' vascular dementia.
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