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Nature Reviews Neurology 3, 590–591 (1 November 2007) | doi:10.1038/ncpneuro0618

Publication bias against negative results from clinical trials: three of the seven deadly sins

Richard T Johnson & Kay Dickersin

There is strong evidence that clinical trials with a positive outcome are more likely to be published than are trials with negative results. In this Viewpoint, Richard Johnson and Kay Dickersin explore the reasons for this phenomenon and discuss possible solutions.