Access

Practice Point

Nature Reviews Neurology 2, 360–361 (1 July 2006) | doi:10.1038/ncpneuro0223

Is a combination of tramadol and acetaminophen effective for the treatment of acute migraine pain?

Zaza Katsarava & Volker Limmroth

Silberstein SD et al. (2005) Tramadol/acetaminophen for the treatment of acute migraine pain: findings of a randomized, placebo-controlled trial. Headache 45: 1317–1327 Synopsis Background Combined tramadol and acetaminophen is effective for treating a variety of acute painful conditions, but little is known about its efficacy in migraine headache.