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Nature Reviews Neurology 2, 585 (1 November 2006) | doi:10.1038/ncpneuro0312

Human prion gene polymorphism influences Wilson's disease onset

Merle U et al. (2006) Influence of homozygosity for methionine at codon 129 of the human prion gene on the onset of neurological and hepatic symptoms in Wilson disease. Arch Neurol 63: 982–985 Studies indicate that the human prion-related protein (PrP) could be involved in copper homeostasis.