FIGURE 1 | Renal biopsy specimen showing focal necrotizing glomerulonephritis in a patient with antineutrophil cytoplasmic antibody (ANCA)-associated microscopic polyangiitis.

From the following article:

Vasculitis syndromes: LAMP-2 illuminates pathogenesis of ANCA glomerulonephritis

Xavier Bosch & Eduard Mirapeix

Nature Reviews Nephrology 5, 247-249 (May 2009)

doi:10.1038/nrneph.2009.51

Vasculitis syndromesLAMP-2 illuminates pathogenesis of ANCA glomerulonephritis

Note the formation of crescents and the glomerular capillary necrosis (hematoxylin and eosin stain; original magnification times400)

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