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Nature Reviews Nephrology 4, 348 (1 July 2008) | doi:10.1038/ncpneph0826

Long-term outcomes after small increases in serum creatinine during hospitalization

Newsome BB et al. (2008) Long-term risk of mortality and end-stage renal disease among the elderly after small increases in serum creatinine level during hospitalization for acute myocardial infarction. Arch Intern Med 168: 609–616 Small increases in serum creatinine level have been associated with an increased risk of adverse short-term outcomes in hospitalized patients, but do such increases correlate with long-term risk of end-stage renal disease (ESRD) and death? To answer this question, Newsome et al. performed a retrospective study of elderly survivors of hospitalization for acute myocardial infarction (AMI).