FIGURE 1  Light microscopy of the patient's kidney biopsy sample.

From the following article:

A case of polyomavirus-associated nephropathy presenting late after transplantation

Shweta Bansal, M Scott Lucia and Alexander Wiseman

Nature Clinical Practice Nephrology (2008) 4, 283-287
doi:10.1038/ncpneph0784

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Figure 1.  Light microscopy of the patient's kidney biopsy sample.

(A) Renal biopsy sample showing glomerular sclerosis, interstitial fibrosis, tubular atrophy (arrowheads), and ongoing interstitial inflammation (arrows; trichrome stain, magnification times200). (B) Renal parenchyma with interstitial nephritis and tubulitis (arrowheads; hematoxylin and eosin stain, magnification times400). Inset showing tubular inflammation with lymphocytes and neutrophils in a tubule with striking polyomavirus nuclear inclusions (arrow; hematoxylin and eosin stain, magnification times600). (C) Immunohistochemistry for simian virus 40 (SV40) antigen showing staining of numerous nuclear viral inclusions (staining for SV40 antigen, magnification times400).

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