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Nature Reviews Nephrology 3, 248–249 (1 May 2007) | doi:10.1038/ncpneph0448

Optimizing automated peritoneal dialysis: increasing nightly dialysate flow vs adding a manual daytime exchange

Simon J Davies

Demetriou D et al. (2006) Adequacy of automated peritoneal dialysis with and without manual daytime exchange: a randomized controlled trial. Kidney Int 70: 1649–1655 Synopsis Background Addition of manual daytime exchanges to automated peritoneal dialysis (APD) regimens optimizes solute clearance, but reduces quality of life and might increase the risk of peritonitis.