Table of contents
November 2006 Volume 2 No 11
Web Collection: Secondary Hyperparathyroidism
Don't miss the FREE Nature Clinical Practice Nephrology online collection. The collection brings together clinically focused articles on hyperparathyroidism secondary to kidney disease, produced by Nature Publishing Group in the past 2 years.
Editorial
Viewpoint
The case for a regulated system of living kidney sales
600The Iranian model of kidney transplantation, whereby donors are paid by a government-sponsored agency, has eliminated the waiting list completely. Elsewhere, black markets for kidneys encourage exploitation of the poor and harm both donors and recipients. As the buying and selling of organs increases relentlessly despite legislation, this author argues that failure to regulate these practices could be considered unethical.
Research Highlights
Cystatin C level predicts heart failure in elderly black individuals with renal disease
602Breast calcification in dialysis patients has a limited effect on mammogram interpretation
602Microalbuminuria in stage 1 hypertension predicted by glomerular hyperfiltration
602Peritoneal dialysate white cell count predicts outcome of peritonitis treatment
603Development of an organ-procurement-organization-based living kidney donation program
603Diabetes mellitus increases the risk of infection following renal transplantation
604Safety of cardiac surgery in kidney transplant recipients
604Blood pressure is increased in living kidney donors
604High prevalence of glomerulopathy in sickle cell anemia
605ARF-specific scoring methods do not predict in-hospital mortality
605Serum CD30 and neopterin predict CAN: impact of immunosuppressant type
606Long-term study of short daily hemodialysis records low levels of morbidity and mortality
606Surgeons with inadequate HBV vaccination underestimate the risk of transmission
607Practice Points
Can plasma iohexol disappearance be used to measure GFR in children with chronic kidney disease?
608Is valsartan renoprotective in patients with IgA nephropathy?
610Does the risk of developing diabetes in hypertensive kidney disease vary with different antihypertensive agents?
612Do elevated homocysteine levels predict mortality in chronic kidney disease stages 3–4?
614Does severe renal insufficiency increase the risk of bleeding after administration of low-molecular-weight heparin?
616Can low doses of contrast agent be safely used for arteriovenous fistula salvage in stage 4 chronic kidney disease?
618Strong association of carotid plaques with mortality and cardiovascular morbidity in hemodialysis patients
620Reviews
Monogenic forms of low-renin hypertension
624Seven single gene mutations are known to cause hypertension, generally by affecting electrolyte transport in the distal nephron, or synthesis or activity of mineralocorticoid hormones. These relatively uncommon disorders should be considered when young patients with a family history of high blood pressure present with severe or refractory hypertension. This article guides clinicians through identification of these defects, their associated laboratory findings, and recommended treatments.
doi:10.1038/ncpneph0309 | Full Text | PDF (277K)
Primer: histopathology of polyomavirus-associated nephropathy in renal allografts
631This short article is an introduction to the histology of damage to transplanted kidneys caused by active BK virus infection. Aimed at trainee pathologists and nephrologists wishing to enhance their understanding of the histological basis of the diseases they manage, this beautifully illustrated paper describes the key features, differential diagnosis and clinical implications of this increasingly frequent complication.
doi:10.1038/ncpneph0319 | Full Text | PDF (713K)
Mechanisms of Disease: the role of GRK4 in the etiology of essential hypertension and salt sensitivity
637Are polymorphisms of the G protein-coupled receptor kinase GRK4 the key to developing new tools for the diagnosis and management of essential hypertension? Here, Felder and Jose explore the therapeutic potential of manipulating this protein, which regulates the activity of the dopamine-1 receptor. The role of GRK4 is set in the context of the contributions of the dopaminergic and renin–angiotensin systems to the pathogenesis of hypertension.
doi:10.1038/ncpneph0301 | Full Text | PDF (325K)
Case Study
Adverse outcomes of renovascular hypertension during pregnancy
651doi:10.1038/ncpneph0310 | Full Text | PDF (296K)
