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Acute kidney injury

Precision perioperative care protects the kidneys

Nature Reviews Nephrology volume 14, pages 8–10 (2018)Cite this article

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Standardized prevention approaches can decrease the incidence of acute kidney injury among high-risk patients. Now, the INPRESS study demonstrates that a personalized intraoperative blood pressure management strategy guided by risk stratification can improve perioperative practice and reduce the risk of organ dysfunction among high-risk patients undergoing major surgery.

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Figure 1: Framework for a platform-adaptive clinical trial for the prevention of perioperative AKI.

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Acknowledgements

The authors thank Daniel Freeman (University of Florida) for his help in drafting the figure. A.B. is supported by R01 GM110240 and P50 GM-111152 from the National Institute of General Medical Sciences.

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Authors and Affiliations

  1. Department of Medicine, Division of Nephrology, Precision and Intelligent Systems in Medicine (PrismaP), Hypertension and Transplantation, University of Florida, Gainesville, 32610–0254, Florida, USA

    Azra Bihorac

  2. Department of Health Services Research, Management and Policy, College of Public Health and Health Professions, University of Florida, Gainesville, 32610–0254, Florida, USA

    Charles E. Hobson

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  1. Azra Bihorac
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  2. Charles E. Hobson
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Correspondence to Azra Bihorac.

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The authors declare no competing financial interests.

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Bihorac, A., Hobson, C. Precision perioperative care protects the kidneys. Nat Rev Nephrol 14, 8–10 (2018). https://doi.org/10.1038/nrneph.2017.170

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