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Chronic kidney disease

Arterial stiffness and renal function—a complex relationship

Nature Reviews Nephrology volume 11, pages 11–13 (2015)Cite this article

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New data suggest that aortic stiffness results in the transmission of excessive flow pulsatility to the renal microcirculation. Further understanding of the mechanisms that regulate the relationship between large arteries and the renal microcirculation could lead to new strategies to protect the kidneys from increased blood pressure load owing to systemic hypertension.

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Authors and Affiliations

  1. Istituto Auxologico Italiano, Laboratory of Cardiovascular Research, Piazza Brescia 20, Milan, 20149, Italy

    Paolo Salvi

  2. Istituto Auxologico Italiano and Department of Health Sciences, University of Milano-Bicocca, Piazza Brescia 20, Milan, 20149, Italy

    Gianfranco Parati

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  1. Paolo Salvi
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  2. Gianfranco Parati
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Correspondence to Paolo Salvi.

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Competing interests

P.S. is a consultant for DiaTecne s.r.l., manufacturer of a pulse wave analysis system. G.P. declares no competing interests.

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Salvi, P., Parati, G. Arterial stiffness and renal function—a complex relationship. Nat Rev Nephrol 11, 11–13 (2015). https://doi.org/10.1038/nrneph.2014.226

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