2007 Research Highlights archive



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Research Highlights archive


2007 Research Highlights archive

Ciclosporin A for the treatment of refractory proteinuria in pediatric lupus nephritis

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0340


Outpatient alcohol cyst sclerotherapy relieves flank pain associated with ADPKD

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0350


Brachio–brachial fistula proposed as an alternative to prosthetic grafts

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0354


COX2 inhibitors: effect on arrhythmia and renal adverse events

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0337


Tranilast for early-stage diabetic nephropathy

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0339


Novel treatment shows promise for type 1 primary hyperoxaluria

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0341


Antiretroviral therapy retards progression of HIV-associated nephropathy

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0353


Study provides strong support for association between cancer and membranous nephropathy

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0351


Fosinopril could reduce cardiovascular events in end-stage renal disease

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0355


Comparing management models for tunneled-cuffed-catheter-related bacteremia

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0338


Low-dose gentamicin effectively prevents catheter-related bacteremia

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0352


Failure to meet targets compromises outcomes of long-term hemodialysis

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0357


Oral hygiene of pediatric renal transplant recipients is improved by sonic toothbrushing

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0358


Cefotaxime lock improves survival of tunneled cuffed hemodialysis catheters in diabetics

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0367


Redox-active iron level predicts viability of renal grafts from non-heart beating donors

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0356


Comparing neuropsychological functioning before and after kidney transplantation

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0365


Three updated Cochrane Reviews evaluate treatment options in chronic kidney disease

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0368


Long-term efficacy of satavaptan in patients with SIADH-related hyponatremia

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0369


A simple score predicts failure of arteriovenous fistulas to mature

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0385


Could polycystic kidneys be used for transplantation?

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0372


Statins do not improve UAE or GFR in subjects with elevated UAE and modest renal impairment

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0388


Advance care planning can give hope to patients with end-stage renal disease

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0390


Vascular brachytherapy—useful for dysfunctional dialysis access grafts?

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0394


RATG reduces risk of pediatric kidney graft thrombosis by decreasing platelet count

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0366


Screening for CKD in the general population

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0386


Tolvaptan increases serum sodium concentrations in hyponatremic patients

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0395


MRI estimates size of normal kidneys more accurately than standard methods

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0414


Is serum NGAL an accurate marker of renal function in pediatric CKD?

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0416


Agalsidase beta slows the progression of advanced Fabry's disease

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0429


Lowering blood pressure could protect against renal dysfunction in type 1 diabetes

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0432


Spironolactone add-on therapy decreases proteinuria in diabetic nephropathy

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0389


Rosiglitazone can be used for diabetes control in hemodialysis patients with hepatitis

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0434


Peritoneal dialysis solution containing amino acids and glucose improves protein synthesis

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0411


Highly variable effects of islet transplantation on renal function in type 1 diabetics

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0417


Cooled dialysate ameliorates hemodialysis-induced left ventricular dysfunction

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0370


Use of an abdominal band reduces postdialytic orthostatic hypotension in some patients

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0387


Survival after cardiac arrest in HD clinic unimproved by access to external defibrillator

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0412


Study supports the use of kidneys and livers donated after cardiac death

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0433


Standardization of end-of-life decision-making in chronic dialysis patients

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0413


Comparing survival of hemodialysis and peritoneal dialysis patients in The Netherlands

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0415


Kidney plus partial liver transplantation: a new option for highly sensitized patients?

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0430


Distalization of the anastomosis reduces high inflow rates in hemodialysis fistulas

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0431


High prevalence of ghost authorship in industry-initiated trials

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0435


High-flux biocompatible dialyzer membranes improve outcome in patients with diabetes

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0454


Patients on dialysis after renal graft failure have increased risk of death

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0455


Adult and female cases of nephrogenic syndrome of inappropriate antidiuresis

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0456


High target hemoglobin levels increase risk of death in CKD patients receiving erythropoietin

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0457


Cigarette smoking is associated with albuminuria in hypertensive adults in the US

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0469


Model identifies individuals at high risk of occult chronic kidney disease

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0482


Falls in systolic blood pressure during hemodialysis relate to good short-term outcome

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0472


Ionic dialysance shows promise for quantification of dialysis dose in acute renal failure

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0474


Weight loss in renal transplant candidates does not improve post-transplantation outcome

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0470


Phosphate binder choice affects risk of death in hemodialysis patients

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0473


Use of a timesheet cuts cold ischemia time of donor kidneys by 8 hours

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0481


Abdominal aortic calcification predicts mortality in hemodialysis patients

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0484


Reprocessing of formalin-fixed tissue for EM precludes accurate TBMN diagnosis

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0458


Mycophenolate mofetil treatment for resistant primary glomerulonephritis

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0459


Cinacalcet not cost-effective in secondary hyperparathyroidism

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0460


Duplex sonography a useful tool for screening patients with suspected renal artery stenosis

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0462


N-terminal probrain natriuretic peptide level predictive of mortality in ESRD

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0485


ARF in the critically ill: CRRT associated with better long-term outcomes than IHD

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0504


Delaying dialysis until after uremic symptoms develop increases mortality risk

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0507


Aspirin lowers S. aureus infection risk in hemodialysis patients with tunneled catheters

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0483


Statin use is associated with a decreased risk of sepsis in patients on dialysis

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0495


Do diuretics improve the survival of patients on hemodialysis?

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0479


Does folic acid reduce cardiovascular deterioration in hemodialysis patients?

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0496


Internal snare maneuver restores catheter patency

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0506


Extrarenal CT angiography findings in potential living kidney donors: costs and consequences

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0497


High prevalence of new-onset hyperglycemia in nondiabetic patients on peritoneal dialysis

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0505


Safety and efficacy of once-daily tacrolimus: 1-year results

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0471


Tacrolimus dose could be individualized according to CYP3A5 genotype

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0503


Histological features of renal allograft biopsies in noncompliant patients

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0480


Severe peritubular capillary basement membrane thickening indicates chronic rejection

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0498


A new dialysis system for premature babies with low birth weight

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0519


pRIFLE: categorizing AKI in critically ill children

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0533


Podocyturia is a marker of preeclampsia

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0535


Graduated fill cycles prevent hydrothorax in children on peritoneal dialysis

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0513


Chronic renal dysfunction after pediatric heart transplantation—risk factors identified

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0534


Tacrolimus monotherapy shows efficacy in membranous nephropathy

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0514


Hematocrit targets at for-profit US dialysis facilities are higher than recommended

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0515


Non-aspirin NSAIDs increase the risk of iron deficiency in hemodialysis patients

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0522


Kidneys can be safely harvested from transfusion-refusing living donors

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0521


Factors that might affect risk of gadodiamide-related nephrogenic systemic fibrosis

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0523


Postoperative heparin not routinely needed in low-risk renal transplant recipients

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0516


A small proportion of living kidney donors experience donation-related insurance problems

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0520


Good outcomes with ABO-incompatible transplantation: report from three centers

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0531


Good long-term outcome with non-heartbeating kidney transplantation

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0532


Nondiabetic renal disease is common in patients with type 2 diabetes

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0544


Whole-gene sequencing for diagnosis of type 1 primary hyperoxaluria

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0546


Eprodisate slows renal function decline in AA amyloidosis

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0550


ACE inhibitors do not delay progression of hypodysplastic nephropathy in children

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0545


Polyflux® 6H dialyzer: a new option for small children requiring dialysis

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0548


Upper arm grafts versus upper arm fistulas following failure of initial forearm fistulas

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0547


Japanese study links hypercalcemia to poor mental health in hemodialysis patients

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0555


Use of kidneys from donors at high risk for HIV or HCV infection should be considered

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0549


Weight loss is associated with reduced urinary albumin excretion

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0556


Typing renal amyloidosis: immunofluorescence staining can be inconclusive

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0566


Heparin-induced thrombocytopenia in the UK hemodialysis population

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0554


Underuse of ACE inhibitors and ARBs in patients with heart failure and renal dysfunction

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0567


Alemtuzumab induction in kidney transplant recipients

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0553


Trimetazidine reduces risk of contrast-induced nephropathy after coronary procedures

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0557


The Framingham equation does not accurately predict cardiac events in the CKD population

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0591


Cystatin C levels are highly predictive of outcome in chronic kidney disease

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0592


Oral antibiotics alone can be used to treat pediatric acute pyelonephritis

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0595


The treatment of severe lupus nephritis with mycophenolate mofetil—a meta-analysis

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0578


Enzyme replacement therapy in patients with Fabry disease and end-stage renal disease

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0579


Machine-generated bicarbonate dialysate customized for patients with acute renal failure

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0593


Intraperitoneal electrolytes in peritoneal dialysis: an alternative to oral supplements?

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0594


Comparing vaccine responses in CNI-treated and sirolimus-treated transplant recipients

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0581


Preserving donated kidneys using machine perfusion improves 5-year allograft survival

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0582


High risk of stroke events in patients with kidney dysfunction

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0580


CKD as a global health problem: KDIGO position statement

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0607


Children with a solitary kidney should avoid riding dirt bikes and all-terrain vehicles

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0619


Presentation and progression of atypical HUS varies with type of complement-gene mutation

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0603


Systematic review of ANCA-associated vasculitis treatments

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0606


Cost-effectiveness of management strategies for renal artery stenosis

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0589


Stoke comorbidity grade predicts survival in ESRD patients on non-dialytic treatment

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0618


Outcomes of access procedures at a high-volume outpatient vascular access center

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0577


Hitting K/DOQI targets—except for blood pressure—reduces mortality in HD patients

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0602


Antibiotic locks not effective against S. aureus catheter-related bacteremia

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0608


CRRT not superior to IRRT in hemodynamically stable patients with acute renal failure

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0588


Intensive insulin therapy associated with reduced risk of AKI in critically ill adults

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0604


High initial tacrolimus dosage recommended in patients switched from ciclosporin

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0590


Body-weight-adjusted mycophenolate mofetil doses in Asian renal transplant recipients

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0605


A diagnostic and treatment algorithm for dense deposit disease

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0645


Frequent nocturnal hemodialysis improves outcomes compared with conventional hemodialysis

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0647


KDOQI update of hemoglobin target

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0649


Measuring hemodialysis vascular access flow by the temperature gradient method

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0629


No apparent benefits of IDPN over oral supplements in malnourished hemodialysis patients

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0644


Homocysteine lowering does not improve survival in advanced CKD or ESRD

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0630


Mortality in hemodialysis patients treated with sevelamer or calcium-based phosphate binders

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0652


Prophylactic hemodialysis prevents renal deterioration after coronary angiography

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0643


Anti-MICA antibodies might contribute to kidney allograft loss

Nature Clinical Practice Nephrology
doi:10.1038/ncpneph0651


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