Abstract

Interest in the functions of microRNAs (miRNAs) in the nervous system has recently expanded to include their roles in neurodegeneration. Investigations have begun to reveal the influence of miRNAs on both neuronal survival and the accumulation of toxic proteins that are associated with neurodegeneration, and are providing clues as to how these toxic proteins can influence miRNA expression.

Author affiliations

1. Stephen M. Eacker, Ted M. Dawson and Valina L. Dawson are at the Neuroregeneration and Stem Cell Programs, the Institute for Cell Engineering and the Department of Neurology at the Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.
2. Ted M. Dawson and Valina L. Dawson are also at the Department of Neuroscience at the Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.
3. Valina L. Dawson is also at the Department of Physiology at the Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.

Correspondence to: Ted M. Dawson^1,2 Email: tdawson@jhmi.edu

Correspondence to: Valina L. Dawson^1,2,3 Email: vdawson@jhmi.edu

Published online 11 November 2009