Table of contents
From the editors
p579 | doi:10.1038/nrn2464
Research Highlights
Fear: Flipping the switch | PDF (265 KB)
p581 | doi:10.1038/nrn2468
In the news
Scanning sexuality | PDF (82 KB)
p582 | doi:10.1038/nrn2454
Dendrites: Ras puts on a spread | PDF (352 KB)
p582 | doi:10.1038/nrn2460
Neurological disorders: Magic with rapamycin | PDF (274 KB)
p582 | doi:10.1038/nrn2467
In brief
Addiction | Spatial processing | Stress response | Sensory systems | PDF (94 KB)
p583 | doi:10.1038/nrn2470
Neurodegenerative disease: High fat lightens the load | PDF (242 KB)
p584 | doi:10.1038/nrn2455
Synaptic plasticity: Retrograde signal is the way forward | PDF (225 KB)
p584 | doi:10.1038/nrn2466
Evolution: Keeping it in the family | PDF (146 KB)
p585 | doi:10.1038/nrn2465
Astrocytes: More than meets the eye | PDF (331 KB)
p586 | doi:10.1038/nrn2458
In brief
Sensory systems | Evolution | Axon guidance | Neuroimaging | PDF (113 KB)
p586 | doi:10.1038/nrn2469
Reviews
Corollary discharge across the animal kingdom
Trinity B. Crapse & Marc A. Sommer
p587 | doi:10.1038/nrn2457
When an animal moves, it must distinguish between sensory inputs caused by its own movement and those caused by another agent. Sommer and Crapse review how corollary discharge, neural signals that travel from the motor to the sensory structures, enable the coordination of movements and sensory analyses across a wide range of species.
'Where' and 'what' in the whisker sensorimotor system
Mathew E. Diamond, Moritz von Heimendahl, Per Magne Knutsen, David Kleinfeld & Ehud Ahissar
p601 | doi:10.1038/nrn2411
Many animals use their whiskers to collect information about the environment. Diamond and colleagues explain how the brain creates a neuronal representation of the location and identity of objects from sensory signals and argue that this involves integration of knowledge about the self-generated whisker motion.
Article series: Memory systems
The parietal cortex and episodic memory: an attentional account
Roberto Cabeza, Elisa Ciaramelli, Ingrid R. Olson & Morris Moscovitch
p613 | doi:10.1038/nrn2459
Conflicting findings from neuroimaging and patient-lesion studies have led to confusion regarding the parietal cortex's contribution to episodic memory. Cabeza and colleagues evaluate the hypotheses that have been put forward to explain these findings and discuss their attention-based hypothesis.
Computer modelling of epilepsy
William W. Lytton
p626 | doi:10.1038/nrn2416
As a dynamical disorder, epilepsy is an attractive target for computer modelling. Here, Lytton provides an overview of the different types of computer model that have been used to describe epilepsy and shows how they can provide new insights into the disorder.
Perspectives
Opinion
How can we realize the promise of personalized antidepressant medicines?
Florian Holsboer
p638 | doi:10.1038/nrn2453
Antidepressant treatments are often selected on a trial-and-error basis, resulting in limited average treatment efficacy. Florian Holsboer argues that combining pharmacogenetic data with biomarkers identified using genomics, proteomics, metabolomics, neuroimaging and neuroendocrinological studies might lead to personalized antidepressant medications with superior efficacy and fewer adverse effects.
Opinion
Culture-sensitive neural substrates of human cognition: a transcultural neuroimaging approach
Shihui Han & Georg Northoff
p646 | doi:10.1038/nrn2456
Psychologists have long known that human cognition and behaviour vary across cultures. Han and Northoff review recent neuroimaging studies which show that one's cultural background also influences the neural activity that underlies cognitive functions.
See also: Correspondence by Kazandjian & Chokron | Correspondence by Han & Northoff
