Table of contents

From the editors

p495 | doi:10.1038/nrn2424


Research Highlights

Neuroimaging: I see what you mean | PDF (678 KB)

p497 | doi:10.1038/nrn2448

Synaptic plasticity: Mothering without smothering | PDF (1,108 KB)

p498 | doi:10.1038/nrn2449

In brief

Epigenetics | Neuroimmunology | Synaptic plasticity | Perception | PDF (94 KB)

p498 | doi:10.1038/nrn2451

Brain–machine interfaces: Getting to grips with a robotic arm | PDF (1,293 KB)

p499 | doi:10.1038/nrn2447

Signalling: Rewarding changes in gene expression | PDF (849 KB)

p499 | doi:10.1038/nrn2450

Sensory systems: Beating the heat | PDF (576 KB)

p500 | doi:10.1038/nrn2419

Neurodegenerative disease: Attacking Huntington's from the inside out | PDF (123 KB)

p500 | doi:10.1038/nrn2425

In the news

Trust in oxytocin | PDF (81 KB)

p500 | doi:10.1038/nrn2446

In brief

Addiction | Neuroeconomics | Molecular neuroscience | Memory | PDF (99 KB)

p501 | doi:10.1038/nrn2452

Stem cells: Waking latent progenitors | PDF (396 KB)

p502 | doi:10.1038/nrn2418

Circadian rhythms: Cycling with cAMP | PDF (542 KB)

p502 | doi:10.1038/nrn2422

Synaptogenesis: What maketh the man? | PDF (360 KB)

p503 | doi:10.1038/nrn2423



Mitochondrial fragmentation in neurodegeneration

Andrew B. Knott, Guy Perkins, Robert Schwarzenbacher & Ella Bossy-Wetzel

p505 | doi:10.1038/nrn2417

There is mounting evidence that mitochondrial dysfunction is an early and causal event in neurodegeneration. Here, Bossy-Wetzel and colleagues discuss how aberrant mitochondrial fission and fusion can contribute to neurodegenerative disease.

Central mechanisms of osmosensation and systemic osmoregulation

Charles W. Bourque

p519 | doi:10.1038/nrn2400

Mammals have evolved a complex set of mechanisms that maintain extracellular fluid osmolality within a narrow range to preserve cellular function. Bourque uncovers the sensory mechanisms, central pathways and peripheral responses that comprise the mammalian osmoregulatory system.

Animal models of Alzheimer's disease and frontotemporal dementia

Jürgen Götz & Lars M. Ittner

p532 | doi:10.1038/nrn2420

Transgenic animal models have been instrumental for the growth of our knowledge about neurodegenerative diseases. Götz and Ittner review what we have learned from the study of mouse, fly and worm models of Alzheimer's disease and frontotemporal dementia.

A framework for studying the neurobiology of value-based decision making

Antonio Rangel, Colin Camerer & P. Read Montague

p545 | doi:10.1038/nrn2357

The past decade has seen an increasing interest in the mechanisms by which the human brain decides what actions to take. Here, Rangel and colleagues provide a framework for the exploration of the neurobiological and computational basis of value-based decision making.




Petilla terminology: nomenclature of features of GABAergic interneurons of the cerebral cortex

Giorgio A. Ascoli, Lidia Alonso-Nanclares, Stewart A. Anderson, German Barrionuevo, Ruth Benavides-Piccione, Andreas Burkhalter, György Buzsáki, Bruno Cauli, Javier DeFelipe, Alfonso Fairén, Dirk Feldmeyer, Gord Fishell, Yves Fregnac, Tamas F. Freund, Daniel Gardner, Esther P. Gardner, Jesse H. Goldberg, Moritz Helmstaedter, Shaul Hestrin, Fuyuki Karube, Zoltán F. Kisvárday, Bertrand Lambolez, David A. Lewis, Oscar Marin, Henry Markram, Alberto Muñoz, Adam Packer, Carl C. H. Petersen, Kathleen S. Rockland, Jean Rossier, Bernardo Rudy, Peter Somogyi, Jochen F. Staiger, Gabor Tamas, Alex M. Thomson, Maria Toledo-Rodriguez, Yun Wang, David C. West & Rafael Yuste for The Petilla Interneuron Nomenclature Group (PING)

p557 | doi:10.1038/nrn2402

Debate continues over how best to classify cortical interneurons. Standardizing the nomenclature used to describe these cells might aid classification efforts. Here, a committee of interneuron researchers propose a standardized set of terms to describe the morphological, molecular and physiological features of an interneuron.

Science and society

Brain foods: the effects of nutrients on brain function

Fernando Gómez-Pinilla

p568 | doi:10.1038/nrn2421

The effects of particular foods on brain function have long been suspected. Gómez-Pinilla discusses the mechanisms responsible for the action of nutrients on mental function and the potential of diet manipulations to promote mental fitness.