Addiction: Lasting impressions | PDF (307 KB)

p409 | doi:10.1038/nrn2399

Neuroimaging: Free will? | PDF (197 KB)

p410 | doi:10.1038/nrn2404

Synaptic transmission: Diffusion to speed up recovery | PDF (268 KB)

p410 | doi:10.1038/nrn2407

Learning: Dabbling in babbling | PDF (276 KB)

p411 | doi:10.1038/nrn2405

Neural circuits: Sing a song of "sex please" | PDF (297 KB)

p412 | doi:10.1038/nrn2396

Neurodegenerative disease: Taking stock of grafts | PDF (194 KB)

p412 | doi:10.1038/nrn2397

Neurodegenerative disease: Inhibiting -secretase where it matters | PDF (338 KB)

p414 | doi:10.1038/nrn2403

Neurogenetics: Understanding deletions | PDF (120 KB)

p414 | doi:10.1038/nrn2406

Neurotransmission: Silence of the synapses | PDF (230 KB)

p415 | doi:10.1038/nrn2408

A technicolour approach to the connectome

Jeff W. Lichtman, Jean Livet & Joshua R. Sanes

p417 | doi:10.1038/nrn2391

New technologies promise to decipher whole-brain connectivity at a much greater resolution than ever before. Here, Lichtman, Livet and Sanes, the creators of Brainbow, critically assess the applications and challenges of this technology and those of other existing and emerging technologies.

• Abstract
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Presynaptic glutamate receptors: physiological functions and mechanisms of action

Paulo S. Pinheiro & Christophe Mulle

p423 | doi:10.1038/nrn2379

Our understanding of the functional roles of presynaptic glutamate receptors continues to grow. Pinheiro and Mulle capture the current state of this knowledge, describing the modes and mechanisms of action of these receptors and the evidence for their contributions to synaptic transmission.

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• PDF (104 KB)

Neuregulin 1 in neural development, synaptic plasticity and schizophrenia

Lin Mei & Wen-Cheng Xiong

p437 | doi:10.1038/nrn2392

Polymorphisms in the genes that encode neuregulin 1 (NRG1) and its receptor ErbB4 have been associated with schizophrenia. Mei and Xiong review the role of NRG1 signalling in neural development and synaptic plasticity and discuss how alterations in NRG1 signalling might contribute to schizophrenia.

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The neural control of micturition

Clare J. Fowler, Derek Griffiths & William C. de Groat

p453 | doi:10.1038/nrn2401

Fowler and colleagues review the pathways and neurotransmitters in the brain, the spinal cord and the peripheral nervous system that regulate the lower urinary tract, and discuss how disruption of the control of micturition leads to incontinence.

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The neural systems that mediate human perceptual decision making

Hauke R. Heekeren, Sean Marrett & Leslie G. Ungerleider

p467 | doi:10.1038/nrn2374

Heekeren and colleagues review neurophysiological and neuroimaging studies of monkeys and humans making perceptual decisions, highlighting both the similarities and the differences in their decision-making processes and providing a new model for the neural architecture that underlies perceptual decision making in humans.

• Abstract
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• PDF (651 KB)