Table of contents
From the editors
p797 | doi:10.1038/nrn2527
Research Highlights
Chemosensation: A behavioural U-turn | PDF (125 KB)
p799 | doi:10.1038/nrn2523
Synaptogenesis: Altering your inhibitions | PDF (146 KB)
p800 | doi:10.1038/nrn2520
Neurodegenerative disease: New ways of tackling A
toxicity | PDF
(149 KB)
p800 | doi:10.1038/nrn2522
In the news
Out of control | PDF (98 KB)
p800 | doi:10.1038/nrn2531
Stem cells: At home with neural stem cells | PDF (155 KB)
p801 | doi:10.1038/nrn2517
Repair: Confounding influence | PDF (135 KB)
p802 | doi:10.1038/nrn2518
Development: The many faces of NKX2-1 | PDF (140 KB)
p802 | doi:10.1038/nrn2519
Attention: The guard and the gate | PDF (143 KB)
p802 | doi:10.1038/nrn2525
In brief
Aging | Circadian rhythms | Behaviour | PDF (129 KB)
p803 | doi:10.1038/nrn2528
Memory: Scaffolding fearful thoughts | PDF (130 KB)
p804 | doi:10.1038/nrn2524
Development: Moving in waves | PDF (153 KB)
p804 | doi:10.1038/nrn2526
Learning: That'll teach you! | PDF (116 KB)
p804 | doi:10.1038/nrn2530
In brief
Feeding behaviour | Development | Neurological disorders | Neuroimmunology | PDF (133 KB)
p805 | doi:10.1038/nrn2529
Progress
C1q: the perfect complement for a synaptic feast?
V. Hugh Perry & Vincent O'Connor
p807 | doi:10.1038/nrn2394
Selective remodelling of synapses contributes to the successful wiring of the nervous system during development. Perry and O'Connor discuss recent studies that have implicated a key component of the immune system, the complement cascade, in this process.
Reviews
Silent synapses and the emergence of a postsynaptic mechanism for LTP
Geoffrey A. Kerchner & Roger A. Nicoll
p813 | doi:10.1038/nrn2501
Silent synapses cannot mediate neurotransmission. Kerchner and Nicoll discuss different mechanisms that have been proposed to underlie synaptic silence, and conclude that LTP and synaptic unsilencing occur by a postsynaptic mechanism that involves AMPA receptor recruitment.
There is a Corrigendum (1 March 2009) associated with this article.
Ubiquitin, the proteasome and protein degradation in neuronal function and dysfunction
Hwan-Ching Tai & Erin M. Schuman
p826 | doi:10.1038/nrn2499
The complex morphology of neurons requires distinctive adaptations for the molecular mechanisms of protein degradation. These are discussed by Tai and Schuman with respect to normal function and dysfunction in neurodegenerative diseases.
Article series: Neuron-glia interactions
Remyelination in the CNS: from biology to therapy
Robin J. M. Franklin & Charles ffrench-Constant
p839 | doi:10.1038/nrn2480
In the CNS, remyelination of denuded axons occurs to reinstate neuronal function. Franklin and ffrench-Constant consider the cells and molecular signals that are required for remyelination and how this knowledge can be channelled towards more effective therapies for demyelinating diseases.
Functional role of the supplementary and pre-supplementary motor areas
Parashkev Nachev, Christopher Kennard & Masud Husain
p856 | doi:10.1038/nrn2478
The supplementary motor complex has a role in regulating action, but whether each of its subregions has a distinct function is unclear. Husain and colleagues review the literature and discuss outstanding issues regarding the function of this complex.
See also: Correspondence by Leek & Johnston | Correspondence by Nachev et al. .
Perspectives
Science and society
Attention and awareness in stage magic: turning tricks into research
Stephen L. Macknik, Mac King, James Randi, Apollo Robbins, Teller, John Thompson & Susana Martinez-Conde
p871 | doi:10.1038/nrn2473
Magic tricks require the manipulation of the audience's attention and awareness. Macknik, Martinez-Conde and their magician co-authors describe the visual and cognitive illusions that underlie many magic tricks, and the techniques that magicians use to achieve these illusions. An interview with Martinez-Conde for Neuropod is available for download.
See also: Correspondence by Lamont & Henderson | Correspondence by Macknik & Martinez-Conde | Correspondence by Lamont & Henderson | Correspondence by Macknik & Martinez-Conde | Correspondence by Lamont & Henderson | Correspondence by Macknik & Martinez-Conde | Correspondence by Lamont & Henderson | Correspondence by Macknik & Martinez-Conde
Viewpoint
Asian promise: the state and future of collaborations in neuroscience
Mu-Ming Poo, Ley Sander, Marc Fivaz & Yasunori Hayashi
p881 | doi:10.1038/nrn2512
As neuroscience research in Asia undergoes unprecedented growth, collaborations are being established between laboratories in Asia and the West. Four neuroscientists describe their experiences of such collaborations and give their input on the challenges and opportunities that they provide.
