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Nature Reviews Neuroscience 9, 804 (1 November 2008) | doi:10.1038/nrn2530

Learning: That'll teach you!

Claudia Wiedemann

In the cerebellum, integration of information at the cellular and systems levels is assumed to be a prerequisite for the learning of motor tasks; however, these levels have not been investigated simultaneously. Now, by analyzing the relationship between Purkinje cell (PC) plasticity and motor learning in awake behaving monkeys, Medina and Lisberger link complex spikes with simple-spike plasticity and learning of a motor task.