Table of contents
May 2007 Vol 8 No 5
From the editors
p321 | doi:10.1038/nrn2146
Research Highlights
Learning and memory: Dynamic DNA methylation
p323 | doi:10.1038/nrn2133
Neurogenesis: Single stress shortens survival
p324 | doi:10.1038/nrn2138
In brief
In brief
p324 | doi:10.1038/nrn2144
Synaptic physiology: The X factor
p325 | doi:10.1038/nrn2136
Neurological disorders: Manic mice turn the clock
p325 | doi:10.1038/nrn2139
Cell fate: Unlocking the right combination
p326 | doi:10.1038/nrn2134
In the news
The Moral Brain
p326 | doi:10.1038/nrn2141
Stem cells: Together we are stronger
p326 | doi:10.1038/nrn2142
In brief
In brief
p327 | doi:10.1038/nrn2145
Evolution: Colour vision for mice
p328 | doi:10.1038/nrn2135
Technology: (Light) remote control of the brain
p328 | doi:10.1038/nrn2143
Behavioural genetics: Turning flies on
p329 | doi:10.1038/nrn2140
Reviews
Transcriptional regulation of vertebrate axon guidance and synapse formation
Franck Polleux, Gulayse Ince-Dunn & Anirvan Ghosh
p331 | doi:10.1038/nrn2118
The formation of complex neuronal circuitry requires precise spatial, temporal and cell-type-specific regulation of the responses of neurons to extracellular guidance and synaptogenic cues. Ghosh and colleagues discuss the key roles of transcription factors in regulating connectivity in the nervous system.
Drosophila olfactory memory: single genes to complex neural circuits
Alex C. Keene & Scott Waddell
p341 | doi:10.1038/nrn2098
Keene and Waddell explore evidence from cutting-edge genetic, imaging and physiological studies and review how the genetic model system of the fly has enabled us to identify the neurons involved and the circuitry of olfactory memory formation and consolidation.
Epigenetic regulation in psychiatric disorders
Nadia Tsankova, William Renthal, Arvind Kumar & Eric J. Nestler
p355 | doi:10.1038/nrn2132
Epigenetic regulation of gene expression occurs in the developing and the mature brain. Nestler and colleagues review recent evidence that epigenetic mechanisms, by causing stable changes in gene expression, are involved in learning and memory and in several psychiatric disorders.
Cell cycle regulation in the postmitotic neuron: oxymoron or new biology?
Karl Herrup & Yan Yang
p368 | doi:10.1038/nrn2124
Once neurogenesis is complete, mature neurons do not divide. Herrup and Yang outline the evidence that, in order to achieve this, adult neurons must constantly hold their cell cycle in check, and discuss the pathological consequences of failure of cell cycle regulation.
Binocular depth perception and the cerebral cortex
Andrew J. Parker
p379 | doi:10.1038/nrn2131
Subtle differences between the images formed by each eye enable us to perceive stereoscopic depth. Parker describes examples of the features of stereoscopic vision that have led to revised hypotheses about the roles of different cortical areas in binocular depth perception.
Perspective
Opinion
The cortical organization of speech processing
Gregory Hickok & David Poeppel
p393 | doi:10.1038/nrn2113
Decades of research have not yet succeeded in definitively characterizing the neuroanatomy of speech processing. Hickok and Poeppel describe a dual-stream model of speech processing and discuss how this model can account for some of the field's paradoxical findings.
