Table of contents


From the editors

p241 | doi:10.1038/nrn2130

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Research Highlights

Neurotransmitters: Axonal release sites discovered

p243 | doi:10.1038/nrn2114

Gene expression: Across the cleft

p244 | doi:10.1038/nrn2125

In brief

Synaptogenesis | Emotion | Brain evolution | Neurological disorders

p244 | doi:10.1038/nrn2127

Repair: Inhibitory signals converge

p245 | doi:10.1038/nrn2116

Repair: Pregnancy (white) matters

p245 | doi:10.1038/nrn2121

Neuronal migration: A migratory stream in the human brain

p246 | doi:10.1038/nrn2115

Neurodegenerative disorders: Weeding out dopaminergic neurons

p246 | doi:10.1038/nrn2122

In the news

Addictive personalities

p246 | doi:10.1038/nrn2129

In brief

Neuroimaging | Stem cells | Neurotransmission | Memory

p247 | doi:10.1038/nrn2128

Cellular neuroscience: Social studies

p248 | doi:10.1038/nrn2120

Neurotransmitter receptors: Location, location, location — a matter of life and death

p248 | doi:10.1038/nrn2126

Synaptic plasticity: Balancing LTP and LTD

p249 | doi:10.1038/nrn2123

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Reviews

The neuronal background K2P channels: focus on TREK1

Eric Honoré

p251 | doi:10.1038/nrn2117

TREK1 is the most extensively studied of the mammalian two-pore-forming K+ channels and is widely expressed in the brain. Honoré reviews the functional properties of TREK1 and describes recent results indicating its important roles in CNS function and disease.

Molecular mechanisms of memory reconsolidation

Natalie C. Tronson & Jane R. Taylor

p262 | doi:10.1038/nrn2090

Memory reconsolidation theory is the subject of intensive recent research and debate. Tronson and Taylor outline the molecular events implicated in this process and discuss how elucidating its mechanisms could improve our understanding of normal and abnormal memory function.

The machinery of colour vision

Samuel G. Solomon & Peter Lennie

p276 | doi:10.1038/nrn2094

The basic principles of colour vision have been understood for a long time, but recent studies have revealed the processes underlying it in more detail. Lennie and Solomon review our current understanding of colour processing, from cones to the primary visual cortex.

Agenesis of the corpus callosum: genetic, developmental and functional aspects of connectivity

Lynn K. Paul, Warren S. Brown, Ralph Adolphs, J. Michael Tyszka, Linda J. Richards, Pratik Mukherjee & Elliott H. Sherr

p287 | doi:10.1038/nrn2107

Agenesis of the corpus callosum (AgCC) shares anatomical and behavioural features with certain neurodevelopmental and psychiatric disorders. Providing insight into the developmental and molecular basis of AgCC, Lynn Paul and colleagues explain why AgCC may be a good model for other brain disorders.

The neurobiology of punishment

Ben Seymour, Tania Singer & Ray Dolan

p300 | doi:10.1038/nrn2119

Humans punish selfishly but also altruistically. Seymour, Singer and Dolan propose a neurobiological model of punishment based on our understanding of motivational systems, observational studies that show how punishment mediates cooperation, and brain imaging data from humans playing economic games.

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Perspective

Opinion

Repair of neural pathways by olfactory ensheathing cells

Geoffrey Raisman & Ying Li

p312 | doi:10.1038/nrn2099

Loss of aligned glial pathways may contribute to the inability of axons to successfully regenerate following CNS injury. Raisman and Li discuss why transplantation of olfactory ensheathing cells might be a promising strategy to re-establish these pathways and restore function.

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