Table of contents
March 2007 Vol 8 No 3
From the editors
p161 | doi:10.1038/nrn2106
Research Highlights
Neural circuit assembly: A molecular matchmaker
p163 | doi:10.1038/nrn2103
Spatial awareness: A goal for place cells
p164 | doi:10.1038/nrn2101
In brief
Memory | Genes and disease | Neuroimaging | Prions
p164 | doi:10.1038/nrn2112
In the news
No smoke without insula
p165 | doi:10.1038/nrn2096
Neuronal migration: Putting 2 and 2 together
p165 | doi:10.1038/nrn2102
Neurogenesis: Recruitment: maturity preferred
p166 | doi:10.1038/nrn2104
Neurodegenerative disorders: Pathways to treatment
p166 | doi:10.1038/nrn2107
Cell fate: I'm the only one you need (for night vision)
p166 | doi:10.1038/nrn2110
Gene expression: Gene expression live on view
p167 | doi:10.1038/nrn2095
Neuroimaging: What counts?
p168 | doi:10.1038/nrn2105
Development: Releasing control
p168 | doi:10.1038/nrn2108
Sleep: Counting orexins
p168 | doi:10.1038/nrn2109
In brief
Neurotransmission | Memory | Neurodegenerative disorders | Cell biology of the neuron
p169 | doi:10.1038/nrn2111
Reviews
The neural circuit of orexin (hypocretin): maintaining sleep and wakefulness
Takeshi Sakurai
p171 | doi:10.1038/nrn2092
Sleep and wakefulness must occur at appropriate times that are in accordance with our internal and external environments. Sakurai reviews how the orexin (hypocretin) system regulates sleep and wakefulness through interactions with systems that control emotion, reward and energy homeostasis.
Neuronal calcium sensor proteins: generating diversity in neuronal Ca2+ signalling
Robert D. Burgoyne
p182 | doi:10.1038/nrn2093
Ca2+ signals in neurons need to be finely tuned in order to trigger the appropriate response. This review discusses the different characteristics and functions of the neuronal calcium sensor protein family members as key components of neuronal Ca2+ signalling pathways.
Neuronal polarity: from extracellular signals to intracellular mechanisms
Nariko Arimura & Kozo Kaibuchi
p194 | doi:10.1038/nrn2056
Differentiation of neurons is accompanied by the development of axons and dendrites. New evidence from in vitro and in vivo studies has led to a model of how extra- and intracellular signalling pathways can establish positive and negative feedback loops for neurite outgrowth.
Cell adhesion molecules: signalling functions at the synapse
Matthew B. Dalva, Andrew C. McClelland & Matthew S. Kayser
p206 | doi:10.1038/nrn2075
Cell adhesion molecules localized at synapses do more than provide a physical link between pre and post-synaptic cells. Dalva and colleagues review the evidence for the roles of these molecules in synaptic development, and in the regulation of synaptic function.
The neuropoietic cytokine family in development, plasticity, disease and injury
Sylvian Bauer, Bradley J. Kerr & Paul H. Patterson
p221 | doi:10.1038/nrn2054
Neuropoietic cytokines are not only important in the immune system. Patterson and colleagues review their wide-ranging functions, in particular their involvement in the control of neuronal, glial and immune responses to injury and disease, and their role in nervous system development.
Perspective
Science and society
The elephant in the room — healthy brains in later life, epidemiology and public health
Carol Brayne
p233 | doi:10.1038/nrn2091
As the average age of the world population constantly increases, ways to prevent dementia have been the focus of many studies. Carol Brayne highlights the difficulties in the interpretation of studies in different population contexts.
Corrigendum: Regulation of cell fate in the sensory epithelia of the inner ear
Matthew W. Kelley
| doi:10.1038/nrn2100
