Review
Nature Reviews Neuroscience 8, 182-193 (March 2007) | doi:10.1038/nrn2093
Neuronal calcium sensor proteins: generating diversity in neuronal Ca2+ signalling
Robert D. Burgoyne1 About the author
Abstract
In neurons, intracellular calcium signals have crucial roles in activating neurotransmitter release and in triggering alterations in neuronal function. Calmodulin has been widely studied as a Ca2+ sensor that has several defined roles in neuronal Ca2+ signalling, but members of the neuronal calcium sensor protein family have also begun to emerge as key components in a number of regulatory pathways and have increased the diversity of neuronal Ca2+ signalling pathways. The differing properties of these proteins allow them to have discrete, non-redundant functions.
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Author affiliations
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The Physiological Laboratory, School of Biomedical Sciences, University of Liverpool, UK.
Email: burgoyne@liv.ac.uk
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