Table of contents
February 2007 Vol 8 No 2
From the editors
p81 | doi:10.1038/nrn2076
Research Highlights
Synaptic physiology: Environmental influences
p82 | doi:10.1038/nrn2079
Neurodegeneration: ApoE receptor 2: a double-edged sword
p83 | doi:10.1038/nrn2081
In brief
Sleep | Decision making | Gene expression | Sensory systems
p83 | doi:10.1038/nrn2087
Learning and memory: Learning through Trk-ing
p84 | doi:10.1038/nrn2077
Neuroimaging: Shopping centres in the brain
p84 | doi:10.1038/nrn2082
In brief
Neurodegenerative disorders | Reward | Prions | Gene expression
p84 | doi:10.1038/nrn2088
Development: Timing the switch
p85 | doi:10.1038/nrn2078
Repair: Long-distance attraction
p86 | doi:10.1038/nrn2080
Sleep and memory: Memory consolidation...while you are sleeping
p86 | doi:10.1038/nrn2084
Neurodegenerative disorders: Accumulating evidence
p87 | doi:10.1038/nrn2083
Neurotransmission: Wrinklefree and deadly: BoNTs
p88 | doi:10.1038/nrn2085
In the news
Follow your nose
p88 | doi:10.1038/nrn2089
Reviews
Spindle regulation in neural precursors of flies and mammals
Joshua J. Buchman & Li-Huei Tsai
p89 | doi:10.1038/nrn2058
The mitotic spindle is crucial for cell division and might have an important role in segregating cell fate determining factors. Buchman and Tsai review studies investigating spindle regulation during Drosophila melanogaster neuroblast mitosis and relate this to our understanding of mammalian neurogenesis.
Regulatory mechanisms of AMPA receptors in synaptic plasticity
Victor A. Derkach, Michael C. Oh, Eric S. Guire & Thomas R. Soderling
p101 | doi:10.1038/nrn2055
Plasticity at central glutamatergic synapses is central to learning and memory and involves alterations in the functional properties and trafficking of synaptic AMPA receptors. The authors provide insights into AMPA receptor regulation and subsequent changes in synaptic strength.
Specification and connectivity of neuronal subtypes in the sensory lineage
Frédéric Marmigère & Patrik Ernfors
p114 | doi:10.1038/nrn2057
The sensory nervous system provides an attractive model in which to study the establishment of neuronal diversity and connectivity. Beginning with neural crest cell migration, Marmigère and Ernfors discuss the molecular basis of specification, survival, axon growth and selection of termination fields.
Lipid raft microdomains and neurotransmitter signalling
John A. Allen, Robyn A. Halverson-Tamboli & Mark M. Rasenick
p128 | doi:10.1038/nrn2059
Lipid rafts — specialized plasma membrane microdomains that are thought to regulate various signalling events — are the focus of intensive research into their roles in the nervous system. Here, Rasenick and colleagues review the evidence for their involvement in regulating neurotransmitter signalling.
Neuronal migration in the adult brain: are we there yet?
H. Troy Ghashghaei, Cary Lai & E. S. Anton
p141 | doi:10.1038/nrn2074
Ensuring that neurons migrate to where they are needed in the brain is essential for the establishment, maintenance and modification of neural circuitry. Anton and colleagues describe how neurons migrate in the postnatal brain, specifically the adult brain.
Perspective
Science and society
Interacting and paradoxical forces in neuroscience and society
Jennifer Singh, Joachim Hallmayer & Judy Illes
p153 | doi:10.1038/nrn2073
Illes and colleagues examine trends in neuroscience discovery, scientific discourse and public reactions to the dissemination of research findings, drawing on the example of a neurogenetic disorder, autism, to investigate the interactions between these groups.
Erratum: How to make a mesodiencephalic dopaminergic neuron
Marten P. Smidt & J. Peter H. Burbach
p160 | doi:10.1038/nrn2086
