Review
Nature Reviews Neuroscience 8, 141-151 (February 2007) | doi:10.1038/nrn2074
Neuronal migration in the adult brain: are we there yet?
H. Troy Ghashghaei1,2, Cary Lai3 & E. S. Anton1 About the authors
Abstract
The generation and targeting of appropriate numbers and types of neurons to where they are needed in the brain is essential for the establishment, maintenance and modification of neural circuitry. This review aims to summarize the patterns, mechanisms and functional significance of neuronal migration in the postnatal brain, with an emphasis on the migratory events that persist in the mature brain.
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Author affiliations
- UNC Neuroscience Center and the Department of Cell and Molecular Physiology, Room 7109B, 103 Mason Farm Road, The University of North Carolina School of Medicine, Chapel Hill, North Carolina 27599-7250, USA.
- Department of Molecular Biomedical Sciences, School of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina 27606, USA.
- Molecular and Integrative Neuroscience Department, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA.
Correspondence to: E. S. Anton1 Email: anton@med.unc.edu
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