Technology: Rainbows in the brain | PDF (200 KB)

p907 | doi:10.1038/nrn2296

Molecular neuroscience: Fat chance of survival | PDF (253 KB)

p908 | doi:10.1038/nrn2287

Learning and memory: ORB2 marks the spot | PDF (155 KB)

p908 | doi:10.1038/nrn2290

Affective disorders: Resisting stress | PDF (211 KB)

p909 | doi:10.1038/nrn2279

Dendrites: Getting to the roots of branches | PDF (385 KB)

p910 | doi:10.1038/nrn2281

Epigenetics: Methylation and schizophrenia | PDF (202 KB)

p910 | doi:10.1038/nrn2282

Sleep: Light sleeper | PDF (204 KB)

p911 | doi:10.1038/nrn2275

Learning and memory: A memorable encounter | PDF (284 KB)

p912 | doi:10.1038/nrn2278

Neuroimaging: Conflicting emotions | PDF (154 KB)

p912 | doi:10.1038/nrn2288

Neurological disorders: Stimulating side effects | PDF (371 KB)

p913 | doi:10.1038/nrn2289

Molecular diversity of Dscam: recognition of molecular identity in neuronal wiring

Dietmar Schmucker

p915 | doi:10.1038/nrn2256

Cell-surface receptors of the Dscam family are required for neuronal wiring in Drosophila. Schmucker discusses the homophilic-binding specificity and diversity of these receptors, their potential role in different aspects of neuronal wiring and key questions that remain unanswered.

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Regulation of ion transport proteins by membrane phosphoinositides

Nikita Gamper & Mark S. Shapiro

p921 | doi:10.1038/nrn2257

Membrane phosphoinositides are important for generating key intracellular second messengers and are also able to directly regulate the activity of membrane proteins. Gamper and Shapiro discuss the regulatory actions of phosphoinositides on a range of neuronal ion channels and transporters.

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Glutamate transporters: confining runaway excitation by shaping synaptic transmission

Anastassios V. Tzingounis & Jacques I. Wadiche

p935 | doi:10.1038/nrn2274

It has become apparent that, in addition to removing excess extracellular glutamate, glutamate transporters can help to shape synaptic events. Tzingounis and Wadiche review the structural properties and regulation of glutamate transporters, highlighting their diverse roles in key brain regions.

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Emerging extranuclear roles of protein SUMOylation in neuronal function and dysfunction

Stéphane Martin, Kevin A. Wilkinson, Atsushi Nishimune & Jeremy M. Henley

p948 | doi:10.1038/nrn2276

Post-translational protein modification can modulate neuronal activity and function. Here, Henley and colleagues discuss the emerging data on the roles of protein SUMOylation in various aspects of nervous-system function and in the pathology of several neurological disorders.

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Evolution of the vertebrate eye: opsins, photoreceptors, retina and eye cup

Trevor D. Lamb, Shaun P. Collin & Edward N. Pugh, Jr

p960 | doi:10.1038/nrn2283

Darwin saw the evolution of the vertebrate eye as one of the biggest challenges for his theory. Lamb and colleagues integrate molecular and morphological evidence across different taxa and propose a sequence of evolutionary steps through which the vertebrate eye might have emerged.

• Abstract
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• Supplementary information