Table of contents
March 2006 Vol 7 No 3
From the editors
p169 | doi:10.1038/nrn1881
Research Highlights
Neurophysiology: Cause for excitement
p171 | doi:10.1038/nrn1873
Neuronal migration: Marching of the neurons
p172 | doi:10.1038/nrn1866
Synaptic physiology: More than a flicker
p172 | doi:10.1038/nrn1877
Neurological diseases: Making steps in stroke therapy
p173 | doi:10.1038/nrn1880
Ministrap: Message in the binding
p174 | doi:10.1038/nrn1864
Development: Eye catching
p174 | doi:10.1038/nrn1878
Psychiatric disorders: Another role for leptin?
p174 | doi:10.1038/nrn1879
In brief
Development | Neurological disorders | Sensory systems | Neuroimmunology
p175 | doi:10.1038/nrn1875
Glia: Changing places
p176 | doi:10.1038/nrn1865
Neurodegenerative diseases: PAK up your troubles
p176 | doi:10.1038/nrn1874
In the news
Timid as a mouse
p176 | doi:10.1038/nrn1876
Development: MicroRNAs mediate synapse development
p177 | doi:10.1038/nrn1863
Reviews
Adult neurogenesis and functional plasticity in neuronal circuits
Pierre-Marie Lledo, Mariana Alonso & Matthew S. Grubb
p179 | doi:10.1038/nrn1867
Lledo and colleagues provide an up-to-date review of recent developments in our understanding of neurogenesis in the adult brain, with a comparative view of the generation of new neurons in the olfactory bulb and the dentate gyrus.
Astrocyte dysfunction in neurological disorders: a molecular perspective
Gerald Seifert, Karl Schilling & Christian Steinhäuser
p194 | doi:10.1038/nrn1870
Astrocytes are not mere 'brain glue', but direct, active communication partners of neurons. Seifert and colleagues discuss their roles in the pathogenesis of several neurological disorders, and argue that these cells might present a therapeutic target in treating these diseases.
Expanding insights of mitochondrial dysfunction in Parkinson's disease
Patrick M. Abou-Sleiman, Miratul M. K. Muqit & Nicholas W. Wood
p207 | doi:10.1038/nrn1868
Mitochondrial dysfunction has long been implicated in Parkinson's disease. Wood and colleagues review recent evidence on the roles of the genes associated with the disease in mitochondrial pathways, highlighting the involvement of oxidative stress in the aetiology of the disorder.
The neural mechanisms of perceptual filling-in
Hidehiko Komatsu
p220 | doi:10.1038/nrn1869
Komatsu provides several striking examples of filling-in — in which a region of the visual field is filled in with the visual attributes of its surround — before considering possible neural mechanisms underlying this remarkable perceptual phenomenon.
Perspectives
Opinion
Looking for inspiration: new perspectives on respiratory rhythm
Jack L. Feldman & Christopher A. Del Negro
p232 | doi:10.1038/nrn1871
Feldman and Del Negro consider recent evidence for two distinct respiratory rhythm generators – the preBötzinger Complex and the retrotrapezoid nucleus/parafacial respiratory group – and underscore the importance of intrinsically rhythmic pacemaker neurons that drive rhythm generation.
Opinion
Towards the neurobiology of emotional body language
Beatrice de Gelder
p242 | doi:10.1038/nrn1872
Emotional body language is a rapidly emerging research field in cognitive neuroscience. de Gelder reviews the body's role in our understanding of emotion, action and communication, and discusses similarities in the neuroanatomy and temporal dynamics between face and body perception.
