Review
Nature Reviews Neuroscience 7, 837-849 (November 2006) | doi:10.1038/nrn1987
There is a Corrigendum (1 March 2007) associated with this article.
Regulation of cell fate in the sensory epithelia of the inner ear
Matthew W. Kelley1 About the author
Abstract
The sensory epithelia of the inner ear contain mechanosensory hair cells and non-sensory supporting cells. Both classes of cell are heterogeneous, with phenotypes varying both between and within epithelia. The specification of individual cells as distinct types of hair cell or supporting cell is regulated through intra- and extracellular signalling pathways that have been poorly understood. However, new methodologies have resulted in significant steps forward in our understanding of the molecular pathways that direct cells towards these cell fates.
- View At a Glance
Author affiliations
-
Section on Developmental Neuroscience, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, 35 Convent Dr., Bethesda, Maryland 20892, USA.
Email: Kelleymt@nidcd.nih.gov
MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated.
NEWS AND VIEWS
Penetrating insights into pore formationNature Structural Biology News and Views (01 Feb 1997)
Exposing the roots of hair cell regeneration in the earNature Medicine News and Views (01 Oct 2003)
See all 8 matches for News And ViewsRESEARCH
Intravenous grafts recapitulate the neurorestoration afforded by intracerebrally delivered multipotent adult progenitor cells in neonatal hypoxic?ischemic ratsJournal of Cerebral Blood Flow & Metabolism Original Article
Lengthening the G1 phase of neural progenitor cells is concurrent with an increase of symmetric neuron generating division after strokeJournal of Cerebral Blood Flow & Metabolism Original Article
See all 64 matches for Research
