FIGURE 1 | Schematic diagram of a glutamatergic synapse.

From the following article:

Neuroenergetics and the kinetic design of excitatory synapses

David Attwell & Alasdair Gibb

Nature Reviews Neuroscience 6, 841-849 (November 2005)

doi:10.1038/nrn1784

Neuroenergetics and the kinetic design of excitatory synapses

Glutamate released from the presynaptic terminal acts on postsynaptic AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid), NMDA (N-methyl-D-aspartate), kainate and metabotropic (mGluR) receptors. The synaptic actions of glutamate are terminated when its concentration in the synaptic cleft is reduced by diffusion, and by uptake by glutamate transporters into surrounding glial cells and into the pre- and postsynaptic neurons.

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