Figures and Tables

From the following article:

Molecular and neuronal substrates for general anaesthetics

Uwe Rudolph & Bernd Antkowiak

Nature Reviews Neuroscience 5, 709-720 (September 2004)

doi:10.1038/nrn1496

Figure 1 - Molecular and neuronal substrates for general anaesthetics

Figure 1

Structural formulae of anaesthetic agents in current clinical use.

Figure 2 - Molecular and neuronal substrates for general anaesthetics

Figure 2

Propofol anaesthesia in humans.

Figure 3 - Molecular and neuronal substrates for general anaesthetics

Figure 3

Synaptic and extrasynaptic locations of GABAA receptors.

Figure 4 - Molecular and neuronal substrates for general anaesthetics

Figure 4

Amino-acid point mutations in beta2(N265S) mice and beta3(N265M) mice.

Figure 5 - Molecular and neuronal substrates for general anaesthetics

Figure 5

Behavioural responses to intravenous anaesthetics in beta3(N265M) and beta2(N265S) mice.

Figure 6 - Molecular and neuronal substrates for general anaesthetics

Figure 6

Proposed roles of GABAA-receptor subtypes and other targets in etomidate and propofol action.